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A phase I dose-escalation clinical trial of intraoperative direct intratumoral injection of HF10 oncolytic virus in non-resectable patients with advanced pancreatic cancer.
Nakao A, Kasuya H, Sahin TT, Nomura N, Kanzaki A, Misawa M, Shirota T, Yamada S, Fujii T, Sugimoto H, Shikano T, Nomoto S, Takeda S, Kodera Y, Nishiyama Y. Nakao A, et al. Among authors: sahin tt. Cancer Gene Ther. 2011 Mar;18(3):167-75. doi: 10.1038/cgt.2010.65. Epub 2010 Nov 19. Cancer Gene Ther. 2011. PMID: 21102422 Clinical Trial.
Antitumor efficacy of oncolytic herpes simplex virus adsorbed onto antigen-specific lymphocytes.
Kanzaki A, Kasuya H, Yamamura K, Sahin TT, Nomura N, Shikano T, Shirota T, Tan G, Fukuda S, Misawa M, Nishikawa Y, Yamada S, Fujii T, Sugimoto H, Nomoto S, Takeda S, Kodera Y, Nakao A. Kanzaki A, et al. Among authors: sahin tt. Cancer Gene Ther. 2012 Apr;19(4):292-8. doi: 10.1038/cgt.2011.91. Epub 2012 Jan 27. Cancer Gene Ther. 2012. PMID: 22281756
Oncolytic herpes virus induces effective anti-cancer immunity against murine colon cancer.
Shirota T, Kasuya H, Kodera Y, Nishikawa Y, Shikano T, Sahin TT, Gewen T, Yamamura K, Fukuda S, Kanzaki A, Yamada S, Fujii T, Sugimoto H, Nomoto S, Takeda S, Nakao A. Shirota T, et al. Among authors: sahin tt. Hepatogastroenterology. 2011 Sep-Oct;58(110-111):1482-9. doi: 10.5754/hge11168. Epub 2011 Jul 15. Hepatogastroenterology. 2011. PMID: 21940320
Combination treatment of human pancreatic cancer xenograft models with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib and oncolytic herpes simplex virus HF10.
Yamamura K, Kasuya H, Sahin TT, Tan G, Hotta Y, Tsurumaru N, Fukuda S, Kanda M, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Fujii T, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Tanaka M, Kodera Y. Yamamura K, et al. Among authors: sahin tt. Ann Surg Oncol. 2014 Feb;21(2):691-8. doi: 10.1245/s10434-013-3329-3. Epub 2013 Oct 30. Ann Surg Oncol. 2014. PMID: 24170435
Combination therapy of oncolytic herpes simplex virus HF10 and bevacizumab against experimental model of human breast carcinoma xenograft.
Tan G, Kasuya H, Sahin TT, Yamamura K, Wu Z, Koide Y, Hotta Y, Shikano T, Yamada S, Kanzaki A, Fujii T, Sugimoto H, Nomoto S, Nishikawa Y, Tanaka M, Tsurumaru N, Kuwahara T, Fukuda S, Ichinose T, Kikumori T, Takeda S, Nakao A, Kodera Y. Tan G, et al. Among authors: sahin tt. Int J Cancer. 2015 Apr 1;136(7):1718-30. doi: 10.1002/ijc.29163. Epub 2014 Sep 27. Int J Cancer. 2015. PMID: 25156870
Combination of the tumor angiogenesis inhibitor bevacizumab and intratumoral oncolytic herpes virus injections as a treatment strategy for human gastric cancers.
Deguchi T, Shikano T, Kasuya H, Nawa A, Fujiwara S, Takeda S, Gewen T, Sahin TT, Yamada S, Kanzaki A, Yamamura K, Fujii T, Sugimoto H, Nomoto S, Fukuda S, Nishikawa Y, Kodera Y, Nakao A. Deguchi T, et al. Among authors: sahin tt. Hepatogastroenterology. 2012 Sep;59(118):1844-50. doi: 10.5754/hge11566. Hepatogastroenterology. 2012. PMID: 22172413
123 results