Doutheau A - Search Results

1

Mechanisms and synthetic modulators of AHL-dependent gene regulation.

Stevens AM, Queneau Y, Soulère L, von Bodman S, Doutheau A. Stevens AM, et al. Among authors: doutheau a. Chem Rev. 2011 Jan 12;111(1):4-27. doi: 10.1021/cr100064s. Epub 2010 Dec 13. Chem Rev. 2011. PMID: 21142091 Review. No abstract available.

2

AHL-dependent quorum sensing inhibition: synthesis and biological evaluation of α-(N-alkyl-carboxamide)-γ-butyrolactones and α-(N-alkyl-sulfonamide)-γ-butyrolactones.

Boukraa M, Sabbah M, Soulère L, El Efrit ML, Queneau Y, Doutheau A. Boukraa M, et al. Among authors: doutheau a. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6876-9. doi: 10.1016/j.bmcl.2011.09.010. Epub 2011 Sep 10. Bioorg Med Chem Lett. 2011. PMID: 21974956

3

Exploring the active site of acyl homoserine lactones-dependent transcriptional regulators with bacterial quorum sensing modulators using molecular mechanics and docking studies.

Soulère L, Frezza M, Queneau Y, Doutheau A. Soulère L, et al. Among authors: doutheau a. J Mol Graph Model. 2007 Sep;26(2):581-90. doi: 10.1016/j.jmgm.2007.04.004. Epub 2007 Apr 21. J Mol Graph Model. 2007. PMID: 17524690

4

N-Acyl-3-amino-5H-furanone derivatives as new inhibitors of LuxR-dependent quorum sensing: Synthesis, biological evaluation and binding mode study.

Estephane J, Dauvergne J, Soulère L, Reverchon S, Queneau Y, Doutheau A. Estephane J, et al. Among authors: doutheau a. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4321-4. doi: 10.1016/j.bmcl.2008.06.090. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18625553

5

Synthesis and biological evaluation of new N-acyl-homoserine-lactone analogues, based on triazole and tetrazole scaffolds, acting as LuxR-dependent quorum sensing modulators.

Sabbah M, Fontaine F, Grand L, Boukraa M, Efrit ML, Doutheau A, Soulère L, Queneau Y. Sabbah M, et al. Among authors: doutheau a. Bioorg Med Chem. 2012 Aug 1;20(15):4727-36. doi: 10.1016/j.bmc.2012.06.007. Epub 2012 Jun 9. Bioorg Med Chem. 2012. PMID: 22748707

6

AHL signaling molecules with a large acyl chain enhance biofilm formation on sulfur and metal sulfides by the bioleaching bacterium Acidithiobacillus ferrooxidans.

González A, Bellenberg S, Mamani S, Ruiz L, Echeverría A, Soulère L, Doutheau A, Demergasso C, Sand W, Queneau Y, Vera M, Guiliani N. González A, et al. Among authors: doutheau a. Appl Microbiol Biotechnol. 2013 Apr;97(8):3729-37. doi: 10.1007/s00253-012-4229-3. Epub 2012 Jul 3. Appl Microbiol Biotechnol. 2013. PMID: 22752316

7

LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones.

Soulère L, Sabbah M, Fontaine F, Queneau Y, Doutheau A. Soulère L, et al. Among authors: doutheau a. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4355-8. doi: 10.1016/j.bmcl.2010.06.081. Epub 2010 Jun 17. Bioorg Med Chem Lett. 2010. PMID: 20615699

8

LuxR dependent quorum sensing inhibition by N,N'-disubstituted imidazolium salts.

Sabbah M, Soulère L, Reverchon S, Queneau Y, Doutheau A. Sabbah M, et al. Among authors: doutheau a. Bioorg Med Chem. 2011 Aug 15;19(16):4868-75. doi: 10.1016/j.bmc.2011.06.075. Epub 2011 Jun 29. Bioorg Med Chem. 2011. PMID: 21782453

9

Synthesis and biological evaluation of homoserine lactone derived ureas as antagonists of bacterial quorum sensing.

Frezza M, Castang S, Estephane J, Soulère L, Deshayes C, Chantegrel B, Nasser W, Queneau Y, Reverchon S, Doutheau A. Frezza M, et al. Among authors: doutheau a. Bioorg Med Chem. 2006 Jul 15;14(14):4781-91. doi: 10.1016/j.bmc.2006.03.017. Epub 2006 Mar 29. Bioorg Med Chem. 2006. PMID: 16574415

10

Ac2-DPD, the bis-(O)-acetylated derivative of 4,5-dihydroxy-2,3-pentanedione (DPD) is a convenient stable precursor of bacterial quorum sensing autoinducer AI-2.

Frezza M, Soulère L, Balestrino D, Gohar M, Deshayes C, Queneau Y, Forestier C, Doutheau A. Frezza M, et al. Among authors: doutheau a. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1428-31. doi: 10.1016/j.bmcl.2006.11.076. Epub 2006 Dec 2. Bioorg Med Chem Lett. 2007. PMID: 17169556

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