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Page 1
Novel, selective CDK9 inhibitors for the treatment of HIV infection.
Németh G, Varga Z, Greff Z, Bencze G, Sipos A, Szántai-Kis C, Baska F, Gyuris A, Kelemenics K, Szathmáry Z, Minárovits J, Kéri G, Orfi L. Németh G, et al. Among authors: greff z. Curr Med Chem. 2011;18(3):342-58. doi: 10.2174/092986711794839188. Curr Med Chem. 2011. PMID: 21143121
Signalling inhibitors against Mycobacterium tuberculosis--early days of a new therapeutic concept in tuberculosis.
Hegymegi-Barakonyi B, Székely R, Varga Z, Kiss R, Borbély G, Németh G, Bánhegyi P, Pató J, Greff Z, Horváth Z, Mészáros G, Marosfalvi J, Erōs D, Szántai-Kis C, Breza N, Garavaglia S, Perozzi S, Rizzi M, Hafenbradl D, Ko M, Av-Gay Y, Klebl BM, Orfi L, Kéri G. Hegymegi-Barakonyi B, et al. Among authors: greff z. Curr Med Chem. 2008;15(26):2760-70. doi: 10.2174/092986708786242886. Curr Med Chem. 2008. PMID: 18991635
Synthesis and evaluation of phosphorus containing, specific CDK9/CycT1 inhibitors.
Németh G, Greff Z, Sipos A, Varga Z, Székely R, Sebestyén M, Jászay Z, Béni S, Nemes Z, Pirat JL, Volle JN, Virieux D, Gyuris Á, Kelemenics K, Ay E, Minarovits J, Szathmary S, Kéri G, Orfi L. Németh G, et al. Among authors: greff z. J Med Chem. 2014 May 22;57(10):3939-65. doi: 10.1021/jm401742r. Epub 2014 May 2. J Med Chem. 2014. PMID: 24742150
Discovery and Biological Evaluation of Novel Dual EGFR/c-Met Inhibitors.
Szokol B, Gyulavári P, Kurkó I, Baska F, Szántai-Kis C, Greff Z, Orfi Z, Peták I, Pénzes K, Torka R, Ullrich A, Orfi L, Vántus T, Kéri G. Szokol B, et al. Among authors: greff z. ACS Med Chem Lett. 2014 Jan 30;5(4):298-303. doi: 10.1021/ml4003309. eCollection 2014 Apr 10. ACS Med Chem Lett. 2014. PMID: 24900830 Free PMC article.
Novel compounds reducing IRS-1 serine phosphorylation for treatment of diabetes.
Simon-Szabó L, Kokas M, Greff Z, Boros S, Bánhegyi P, Zsákai L, Szántai-Kis C, Vantus T, Mandl J, Bánhegyi G, Vályi-Nagy I, Őrfi L, Ullrich A, Csala M, Kéri G. Simon-Szabó L, et al. Among authors: greff z. Bioorg Med Chem Lett. 2016 Jan 15;26(2):424-428. doi: 10.1016/j.bmcl.2015.11.099. Epub 2015 Nov 28. Bioorg Med Chem Lett. 2016. PMID: 26704265
Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.
Brägelmann J, Dammert MA, Dietlein F, Heuckmann JM, Choidas A, Böhm S, Richters A, Basu D, Tischler V, Lorenz C, Habenberger P, Fang Z, Ortiz-Cuaran S, Leenders F, Eickhoff J, Koch U, Getlik M, Termathe M, Sallouh M, Greff Z, Varga Z, Balke-Want H, French CA, Peifer M, Reinhardt HC, Örfi L, Kéri G, Ansén S, Heukamp LC, Büttner R, Rauh D, Klebl BM, Thomas RK, Sos ML. Brägelmann J, et al. Among authors: greff z. Cell Rep. 2017 Sep 19;20(12):2833-2845. doi: 10.1016/j.celrep.2017.08.082. Cell Rep. 2017. PMID: 28930680 Free PMC article.
Drug discovery in the kinase inhibitory field using the Nested Chemical Library technology.
Kéri G, Székelyhidi Z, Bánhegyi P, Varga Z, Hegymegi-Barakonyi B, Szántai-Kis C, Hafenbradl D, Klebl B, Muller G, Ullrich A, Erös D, Horváth Z, Greff Z, Marosfalvi J, Pató J, Szabadkai I, Szilágyi I, Szegedi Z, Varga I, Wáczek F, Orfi L. Kéri G, et al. Among authors: greff z. Assay Drug Dev Technol. 2005 Oct;3(5):543-51. doi: 10.1089/adt.2005.3.543. Assay Drug Dev Technol. 2005. PMID: 16305311 Review.
22 results