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Page 1
The German etanercept registry for treatment of juvenile idiopathic arthritis.
Horneff G, Schmeling H, Biedermann T, Foeldvari I, Ganser G, Girschick HJ, Hospach T, Huppertz HI, Keitzer R, Küster RM, Michels H, Moebius D, Rogalski B, Thon A; Paediatric Rheumatology Collaborative Group. Horneff G, et al. Among authors: moebius d. Ann Rheum Dis. 2004 Dec;63(12):1638-44. doi: 10.1136/ard.2003.014886. Epub 2004 Apr 28. Ann Rheum Dis. 2004. PMID: 15115709 Free PMC article. Review.
Safety and efficacy of combination of etanercept and methotrexate compared to treatment with etanercept only in patients with juvenile idiopathic arthritis (JIA): preliminary data from the German JIA Registry.
Horneff G, De Bock F, Foeldvari I, Girschick HJ, Michels H, Moebius D, Schmeling H; German and Austrian Paediatric Rheumatology Collaborative Study Group. Horneff G, et al. Among authors: moebius d. Ann Rheum Dis. 2009 Apr;68(4):519-25. doi: 10.1136/ard.2007.087593. Epub 2008 Apr 15. Ann Rheum Dis. 2009. PMID: 18413440 Clinical Trial.
B cell depletion for autoimmune diseases in paediatric patients.
Jansson AF, Sengler C, Kuemmerle-Deschner J, Gruhn B, Kranz AB, Lehmann H, Kleinert D, Pape L, Girschick HJ, Foeldvari I, Haffner D, Haas JP, Moebius D, Foell D, Peitz J, Grote V. Jansson AF, et al. Among authors: moebius d. Clin Rheumatol. 2011 Jan;30(1):87-97. doi: 10.1007/s10067-010-1630-0. Epub 2010 Dec 1. Clin Rheumatol. 2011. PMID: 21120559
Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility.
Romero A, Ashcraft L, Chandra A, DiMassa V, Cremin P, Collibee SE, Chuang C, Hartman J, Hwee DT, St Jean D, Malinowski J, DeBenedetto M, Moebius D, Payette J, Vargas R, Yeoman J, Motani A, Reagan J, Malik FI, Morgan BP. Romero A, et al. Among authors: moebius d. J Med Chem. 2024 May 23;67(10):7825-7835. doi: 10.1021/acs.jmedchem.3c02413. Epub 2024 May 10. J Med Chem. 2024. PMID: 38729623 Free PMC article.
Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2 S,3 R)- N-(( S)-3-(Cyclopent-1-en-1-yl)-1-(( R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-(( S)-2-(2-morpholinoacetamido)propanamido)propenamide).
Johnson HWB, Lowe E, Anderl JL, Fan A, Muchamuel T, Bowers S, Moebius DC, Kirk C, McMinn DL. Johnson HWB, et al. Among authors: moebius dc. J Med Chem. 2018 Dec 27;61(24):11127-11143. doi: 10.1021/acs.jmedchem.8b01201. Epub 2018 Dec 11. J Med Chem. 2018. PMID: 30380863
Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit.
Johnson HWB, Anderl JL, Bradley EK, Bui J, Jones J, Arastu-Kapur S, Kelly LM, Lowe E, Moebius DC, Muchamuel T, Kirk C, Wang Z, McMinn D. Johnson HWB, et al. Among authors: moebius dc. ACS Med Chem Lett. 2017 Mar 9;8(4):413-417. doi: 10.1021/acsmedchemlett.6b00496. eCollection 2017 Apr 13. ACS Med Chem Lett. 2017. PMID: 28435528 Free PMC article.
Total Synthesis of (-)-Nemorosone and (+)-Secohyperforin.
Sparling BA, Tucker JK, Moebius DC, Shair MD. Sparling BA, et al. Among authors: moebius dc. Org Lett. 2015 Jul 17;17(14):3398-401. doi: 10.1021/acs.orglett.5b01121. Epub 2015 Jun 30. Org Lett. 2015. PMID: 26125288
Enantioselective total synthesis of hyperforin.
Sparling BA, Moebius DC, Shair MD. Sparling BA, et al. Among authors: moebius dc. J Am Chem Soc. 2013 Jan 16;135(2):644-7. doi: 10.1021/ja312150d. Epub 2012 Dec 31. J Am Chem Soc. 2013. PMID: 23270309
16 results