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Progressive but previously untreated CLL patients with greater array CGH complexity exhibit a less durable response to chemoimmunotherapy.
Kay NE, Eckel-Passow JE, Braggio E, Vanwier S, Shanafelt TD, Van Dyke DL, Jelinek DF, Tschumper RC, Kipps T, Byrd JC, Fonseca R. Kay NE, et al. Among authors: fonseca r. Cancer Genet Cytogenet. 2010 Dec;203(2):161-8. doi: 10.1016/j.cancergencyto.2010.09.003. Cancer Genet Cytogenet. 2010. PMID: 21156228 Free PMC article.
Deletions of 17p13.1 and 13q14 are uncommon in Waldenström macroglobulinemia clonal cells and mostly seen at the time of disease progression.
Schop RF, Jalal SM, Van Wier SA, Ahmann GJ, Bailey RJ, Kyle RA, Greipp PR, Rajkumar SV, Gertz MA, Lust JA, Lacy MQ, Dispenzieri A, Witzig TE, Fonseca R. Schop RF, et al. Among authors: fonseca r. Cancer Genet Cytogenet. 2002 Jan 1;132(1):55-60. doi: 10.1016/s0165-4608(01)00526-x. Cancer Genet Cytogenet. 2002. PMID: 11801310
A validated FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS.
Chng WJ, Van Wier SA, Ahmann GJ, Winkler JM, Jalal SM, Bergsagel PL, Chesi M, Trendle MC, Oken MM, Blood E, Henderson K, Santana-Dávila R, Kyle RA, Gertz MA, Lacy MQ, Dispenzieri A, Greipp PR, Fonseca R. Chng WJ, et al. Among authors: fonseca r. Blood. 2005 Sep 15;106(6):2156-61. doi: 10.1182/blood-2005-02-0761. Epub 2005 May 26. Blood. 2005. PMID: 15920009 Free PMC article.
1,487 results