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The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss.
Pratap J, Akech J, Wixted JJ, Szabo G, Hussain S, McGee-Lawrence ME, Li X, Bedard K, Dhillon RJ, van Wijnen AJ, Stein JL, Stein GS, Westendorf JJ, Lian JB. Pratap J, et al. Mol Cancer Ther. 2010 Dec;9(12):3210-20. doi: 10.1158/1535-7163.MCT-10-0572. Mol Cancer Ther. 2010. PMID: 21159607 Free PMC article.
Integrin αvβ6 promotes an osteolytic program in cancer cells by upregulating MMP2.
Dutta A, Li J, Lu H, Akech J, Pratap J, Wang T, Zerlanko BJ, FitzGerald TJ, Jiang Z, Birbe R, Wixted J, Violette SM, Stein JL, Stein GS, Lian JB, Languino LR. Dutta A, et al. Among authors: pratap j. Cancer Res. 2014 Mar 1;74(5):1598-608. doi: 10.1158/0008-5472.CAN-13-1796. Epub 2014 Jan 2. Cancer Res. 2014. PMID: 24385215 Free PMC article.
Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions.
Akech J, Wixted JJ, Bedard K, van der Deen M, Hussain S, Guise TA, van Wijnen AJ, Stein JL, Languino LR, Altieri DC, Pratap J, Keller E, Stein GS, Lian JB. Akech J, et al. Among authors: pratap j. Oncogene. 2010 Feb 11;29(6):811-21. doi: 10.1038/onc.2009.389. Epub 2009 Nov 16. Oncogene. 2010. PMID: 19915614 Free PMC article.
In situ immunofluorescence analysis: immunofluorescence microscopy.
Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Javed A, et al. Among authors: pratap j. Methods Mol Biol. 2004;285:23-8. doi: 10.1385/1-59259-822-6:023. Methods Mol Biol. 2004. PMID: 15269392 No abstract available.
Immunofluorescence analysis using epitope-tagged proteins: in vitro system.
Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Javed A, et al. Among authors: pratap j. Methods Mol Biol. 2004;285:33-6. doi: 10.1385/1-59259-822-6:033. Methods Mol Biol. 2004. PMID: 15269394 No abstract available.
133 results