Hirai H - Search Results

1

Rakicidin A effectively induces apoptosis in hypoxia adapted Bcr-Abl positive leukemic cells.

Takeuchi M, Ashihara E, Yamazaki Y, Kimura S, Nakagawa Y, Tanaka R, Yao H, Nagao R, Hayashi Y, Hirai H, Maekawa T. Takeuchi M, et al. Among authors: hirai h. Cancer Sci. 2011 Mar;102(3):591-6. doi: 10.1111/j.1349-7006.2010.01813.x. Epub 2010 Dec 19. Cancer Sci. 2011. PMID: 21166958 Free article.

2

A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro.

Kawata E, Ashihara E, Nakagawa Y, Kiuchi T, Ogura M, Yao H, Sakai K, Tanaka R, Nagao R, Yokota A, Takeuchi M, Kimura S, Hirai H, Maekawa T. Kawata E, et al. Among authors: hirai h. Cancer Lett. 2010 Aug 28;294(2):245-53. doi: 10.1016/j.canlet.2010.02.008. Epub 2010 Mar 4. Cancer Lett. 2010. PMID: 20206440 Free article.

3

Rapid automated detection of ABL kinase domain mutations in imatinib-resistant patients.

Tanaka R, Kimura S, Ashihara E, Yoshimura M, Takahashi N, Wakita H, Itoh K, Nishiwaki K, Suzuki K, Nagao R, Yao H, Hayashi Y, Satake S, Hirai H, Sawada K, Ottmann OG, Melo JV, Maekawa T. Tanaka R, et al. Among authors: hirai h. Cancer Lett. 2011 Dec 22;312(2):228-34. doi: 10.1016/j.canlet.2011.08.009. Epub 2011 Aug 22. Cancer Lett. 2011. PMID: 21890264

4

Growth inhibition of imatinib-resistant CML cells with the T315I mutation and hypoxia-adaptation by AV65--a novel Wnt/β-catenin signaling inhibitor.

Nagao R, Ashihara E, Kimura S, Strovel JW, Yao H, Takeuchi M, Tanaka R, Hayashi Y, Hirai H, Padia J, Strand K, Maekawa T. Nagao R, et al. Among authors: hirai h. Cancer Lett. 2011 Dec 15;312(1):91-100. doi: 10.1016/j.canlet.2011.08.002. Epub 2011 Aug 17. Cancer Lett. 2011. PMID: 21906872 Free article.

5

Non-steady-state hematopoiesis regulated by the C/EBPβ transcription factor.

Hirai H, Yokota A, Tamura A, Sato A, Maekawa T. Hirai H, et al. Cancer Sci. 2015 Jul;106(7):797-802. doi: 10.1111/cas.12690. Epub 2015 Jun 1. Cancer Sci. 2015. PMID: 25940801 Free PMC article.

6

C/EBPβ promotes BCR-ABL-mediated myeloid expansion and leukemic stem cell exhaustion.

Hayashi Y, Hirai H, Kamio N, Yao H, Yoshioka S, Miura Y, Ashihara E, Fujiyama Y, Tenen DG, Maekawa T. Hayashi Y, et al. Among authors: hirai h. Leukemia. 2013 Mar;27(3):619-28. doi: 10.1038/leu.2012.258. Epub 2012 Sep 5. Leukemia. 2013. PMID: 22948537 Free PMC article.

7

Galectin-9 ameliorates acute GVH disease through the induction of T-cell apoptosis.

Sakai K, Kawata E, Ashihara E, Nakagawa Y, Yamauchi A, Yao H, Nagao R, Tanaka R, Yokota A, Takeuchi M, Hirai H, Kimura S, Hirashima M, Yoshimura N, Maekawa T. Sakai K, et al. Among authors: hirai h. Eur J Immunol. 2011 Jan;41(1):67-75. doi: 10.1002/eji.200939931. Epub 2010 Dec 9. Eur J Immunol. 2011. PMID: 21182078 Free article.

8

Multiple myeloma cells adapted to long-exposure of hypoxia exhibit stem cell characters with TGF-β/Smad pathway activation.

Nakagawa Y, Ashihara E, Yao H, Yokota A, Toda Y, Miura Y, Nakata S, Hirai H, Maekawa T. Nakagawa Y, et al. Among authors: hirai h. Biochem Biophys Res Commun. 2018 Feb 5;496(2):490-496. doi: 10.1016/j.bbrc.2018.01.034. Epub 2018 Jan 6. Biochem Biophys Res Commun. 2018. PMID: 29309790

9

C/EBPβ is a critical mediator of IFN-α-induced exhaustion of chronic myeloid leukemia stem cells.

Yokota A, Hirai H, Sato R, Adachi H, Sato F, Hayashi Y, Sato A, Kamio N, Miura Y, Nakano M, Tenen DG, Kimura S, Tashiro K, Maekawa T. Yokota A, et al. Among authors: hirai h. Blood Adv. 2019 Feb 12;3(3):476-488. doi: 10.1182/bloodadvances.2018020503. Blood Adv. 2019. PMID: 30755436 Free PMC article.

10

Targeting DNMT1 by demethylating agent OR-2100 increases tyrosine kinase inhibitors-sensitivity and depletes leukemic stem cells in chronic myeloid leukemia.

Kamachi K, Ureshino H, Watanabe T, Yoshida N, Yamamoto Y, Kurahashi Y, Fukuda-Kurahashi Y, Hayashi Y, Hirai H, Yamashita S, Ushijima T, Okada S, Kimura S. Kamachi K, et al. Among authors: hirai h. Cancer Lett. 2022 Feb 1;526:273-283. doi: 10.1016/j.canlet.2021.11.032. Epub 2021 Dec 4. Cancer Lett. 2022. PMID: 34875342 Free article.

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