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Clevudine-induced viral response, associated with continued reduction of HBsAg titer, was durable after the withdrawal of therapy.
Lee HS, Yoo BC, Lee KS, Kim JH, Um SH, Ryu SH, Lee YS, Kim YS, Yoo K, Han JY, Hwang JS, Kim TH, Yang JM, Lee HJ, Chon CY, Cho M, Han BH, Hwang SG, Byun KS, Chung YH, Cho SH, Koh KC, Kim BI, Kim HC, Paik SW, Lee MS, Yoo HW, Han CJ. Lee HS, et al. Among authors: kim th, kim bi, kim ys, kim hc, kim jh. J Gastroenterol. 2011 Mar;46(3):410-4. doi: 10.1007/s00535-010-0354-x. Epub 2010 Dec 23. J Gastroenterol. 2011. PMID: 21181212
Twenty-four-week clevudine therapy showed potent and sustained antiviral activity in HBeAg-positive chronic hepatitis B.
Yoo BC, Kim JH, Chung YH, Lee KS, Paik SW, Ryu SH, Han BH, Han JY, Byun KS, Cho M, Lee HJ, Kim TH, Cho SH, Park JW, Um SH, Hwang SG, Kim YS, Lee YJ, Chon CY, Kim BI, Lee YS, Yang JM, Kim HC, Hwang JS, Choi SK, Kweon YO, Jeong SH, Lee MS, Choi JY, Kim DG, Kim YS, Lee HY, Yoo K, Yoo HW, Lee HS. Yoo BC, et al. Among authors: kim dg, kim th, kim bi, kim ys, kim hc, kim jh. Hepatology. 2007 May;45(5):1172-8. doi: 10.1002/hep.21629. Hepatology. 2007. PMID: 17464992 Clinical Trial.
[A comparative cross-sectional study of the development of hepatocellular carcinoma in patients with liver cirrhosis caused by hepatitis B virus, alcohol, or combination of hepatitis b virus and alcohol].
Chung NS, Kwon OS, Park CH, Kim YN, Cho GH, Lee JJ, Kim GH, Kim HO, Ko KI, Yu SK, Kwon KA, Kim YS, Choi DJ, Kim JH. Chung NS, et al. Among authors: kim gh, kim yn, kim ho, kim ys, kim jh. Korean J Gastroenterol. 2007 Jun;49(6):369-75. Korean J Gastroenterol. 2007. PMID: 17641555 Korean.
Clevudine is highly efficacious in hepatitis B e antigen-negative chronic hepatitis B with durable off-therapy viral suppression.
Yoo BC, Kim JH, Kim TH, Koh KC, Um SH, Kim YS, Lee KS, Han BH, Chon CY, Han JY, Ryu SH, Kim HC, Byun KS, Hwang SG, Kim BI, Cho M, Yoo K, Lee HJ, Hwang JS, Kim YS, Lee YS, Choi SK, Lee YJ, Yang JM, Park JW, Lee MS, Kim DG, Chung YH, Cho SH, Choi JY, Kweon YO, Lee HY, Jeong SH, Yoo HW, Lee HS. Yoo BC, et al. Among authors: kim dg, kim th, kim bi, kim ys, kim hc, kim jh. Hepatology. 2007 Oct;46(4):1041-8. doi: 10.1002/hep.21800. Hepatology. 2007. PMID: 17647293 Clinical Trial.
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