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Dipeptidylpeptidase IV (DPIV) and alanyl-aminopeptidases (AAPs) as a new target complex for treatment of autoimmune and inflammatory diseases-proof of concept in a mouse model of colitis.
Bank U, Tadje J, Helmuth M, Stefin S, Täger M, Wolke C, Wischeropp A, Ittenson A, Reinhold D, Ansorge S, Lendeckel U. Bank U, et al. Among authors: helmuth m. Adv Exp Med Biol. 2006;575:143-53. doi: 10.1007/0-387-32824-6_15. Adv Exp Med Biol. 2006. PMID: 16700517 No abstract available.
Possible role of DP IV inhibitors in acne therapy.
Thielitz A, Reinhold D, Vetter R, Lendeckel U, Kähne T, Bank U, Helmuth M, Neubert K, Faust J, Hartig R, Wrenger S, Zouboulis CC, Ansorge S, Gollnick H. Thielitz A, et al. Among authors: helmuth m. Adv Exp Med Biol. 2006;575:163-7. doi: 10.1007/0-387-32824-6_17. Adv Exp Med Biol. 2006. PMID: 16700519 No abstract available.
Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiation.
Thielitz A, Reinhold D, Vetter R, Bank U, Helmuth M, Hartig R, Wrenger S, Wiswedel I, Lendeckel U, Kähne T, Neubert K, Faust J, Zouboulis CC, Ansorge S, Gollnick H. Thielitz A, et al. Among authors: helmuth m. J Invest Dermatol. 2007 May;127(5):1042-51. doi: 10.1038/sj.jid.5700439. Epub 2006 Jun 15. J Invest Dermatol. 2007. PMID: 16778789 Free article.
Triggering endogenous immunosuppressive mechanisms by combined targeting of Dipeptidyl peptidase IV (DPIV/CD26) and Aminopeptidase N (APN/ CD13)--a novel approach for the treatment of inflammatory bowel disease.
Bank U, Heimburg A, Helmuth M, Stefin S, Lendeckel U, Reinhold D, Faust J, Fuchs P, Sens B, Neubert K, Täger M, Ansorge S. Bank U, et al. Among authors: helmuth m. Int Immunopharmacol. 2006 Dec 20;6(13-14):1925-34. doi: 10.1016/j.intimp.2006.09.014. Epub 2006 Oct 17. Int Immunopharmacol. 2006. PMID: 17161345
72 results