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Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies.
Hu-Lowe DD, Chen E, Zhang L, Watson KD, Mancuso P, Lappin P, Wickman G, Chen JH, Wang J, Jiang X, Amundson K, Simon R, Erbersdobler A, Bergqvist S, Feng Z, Swanson TA, Simmons BH, Lippincott J, Casperson GF, Levin WJ, Stampino CG, Shalinsky DR, Ferrara KW, Fiedler W, Bertolini F. Hu-Lowe DD, et al. Among authors: ferrara kw. Cancer Res. 2011 Feb 15;71(4):1362-73. doi: 10.1158/0008-5472.CAN-10-1451. Epub 2011 Jan 6. Cancer Res. 2011. PMID: 21212415 Free PMC article.
Ultrasound increases nanoparticle delivery by reducing intratumoral pressure and increasing transport in epithelial and epithelial-mesenchymal transition tumors.
Watson KD, Lai CY, Qin S, Kruse DE, Lin YC, Seo JW, Cardiff RD, Mahakian LM, Beegle J, Ingham ES, Curry FR, Reed RK, Ferrara KW. Watson KD, et al. Among authors: ferrara kw. Cancer Res. 2012 Mar 15;72(6):1485-93. doi: 10.1158/0008-5472.CAN-11-3232. Epub 2012 Jan 26. Cancer Res. 2012. PMID: 22282664 Free PMC article.
Copper-doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity.
Kheirolomoom A, Mahakian LM, Lai CY, Lindfors HA, Seo JW, Paoli EE, Watson KD, Haynam EM, Ingham ES, Xing L, Cheng RH, Borowsky AD, Cardiff RD, Ferrara KW. Kheirolomoom A, et al. Among authors: ferrara kw. Mol Pharm. 2010 Dec 6;7(6):1948-58. doi: 10.1021/mp100245u. Mol Pharm. 2010. PMID: 20925429 Free PMC article.
Dynamic imaging of arginine-rich heart-targeted vehicles in a mouse model.
Zhang H, Kusunose J, Kheirolomoom A, Seo JW, Qi J, Watson KD, Lindfors HA, Ruoslahti E, Sutcliffe JL, Ferrara KW. Zhang H, et al. Among authors: ferrara kw. Biomaterials. 2008 Apr;29(12):1976-88. doi: 10.1016/j.biomaterials.2007.12.033. Epub 2008 Feb 6. Biomaterials. 2008. PMID: 18255141 Free PMC article.
216 results