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Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice.
Franco AT, Malaguarnera R, Refetoff S, Liao XH, Lundsmith E, Kimura S, Pritchard C, Marais R, Davies TF, Weinstein LS, Chen M, Rosen N, Ghossein R, Knauf JA, Fagin JA. Franco AT, et al. Among authors: malaguarnera r. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1615-20. doi: 10.1073/pnas.1015557108. Epub 2011 Jan 10. Proc Natl Acad Sci U S A. 2011. PMID: 21220306 Free PMC article.
BRAFV600E mutation is associated with preferential sensitivity to mitogen-activated protein kinase kinase inhibition in thyroid cancer cell lines.
Leboeuf R, Baumgartner JE, Benezra M, Malaguarnera R, Solit D, Pratilas CA, Rosen N, Knauf JA, Fagin JA. Leboeuf R, et al. Among authors: malaguarnera r. J Clin Endocrinol Metab. 2008 Jun;93(6):2194-201. doi: 10.1210/jc.2007-2825. Epub 2008 Apr 1. J Clin Endocrinol Metab. 2008. PMID: 18381570 Free PMC article.
The RET kinase inhibitor NVP-AST487 blocks growth and calcitonin gene expression through distinct mechanisms in medullary thyroid cancer cells.
Akeno-Stuart N, Croyle M, Knauf JA, Malaguarnera R, Vitagliano D, Santoro M, Stephan C, Grosios K, Wartmann M, Cozens R, Caravatti G, Fabbro D, Lane HA, Fagin JA. Akeno-Stuart N, et al. Among authors: malaguarnera r. Cancer Res. 2007 Jul 15;67(14):6956-64. doi: 10.1158/0008-5472.CAN-06-4605. Cancer Res. 2007. PMID: 17638907
HMGA1 inhibits the function of p53 family members in thyroid cancer cells.
Frasca F, Rustighi A, Malaguarnera R, Altamura S, Vigneri P, Del Sal G, Giancotti V, Pezzino V, Vigneri R, Manfioletti G. Frasca F, et al. Among authors: malaguarnera r. Cancer Res. 2006 Mar 15;66(6):2980-9. doi: 10.1158/0008-5472.CAN-05-2637. Cancer Res. 2006. PMID: 16540646 Free article.
62 results