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MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival.
Afanasyeva EA, Mestdagh P, Kumps C, Vandesompele J, Ehemann V, Theissen J, Fischer M, Zapatka M, Brors B, Savelyeva L, Sagulenko V, Speleman F, Schwab M, Westermann F. Afanasyeva EA, et al. Among authors: vandesompele j. Cell Death Differ. 2011 Jun;18(6):974-84. doi: 10.1038/cdd.2010.164. Epub 2011 Jan 14. Cell Death Differ. 2011. PMID: 21233845 Free PMC article.
MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors.
Mestdagh P, Fredlund E, Pattyn F, Schulte JH, Muth D, Vermeulen J, Kumps C, Schlierf S, De Preter K, Van Roy N, Noguera R, Laureys G, Schramm A, Eggert A, Westermann F, Speleman F, Vandesompele J. Mestdagh P, et al. Among authors: vandesompele j. Oncogene. 2010 Mar 4;29(9):1394-404. doi: 10.1038/onc.2009.429. Epub 2009 Nov 30. Oncogene. 2010. PMID: 19946337
Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo.
Lambertz I, Nittner D, Mestdagh P, Denecker G, Vandesompele J, Dyer MA, Marine JC. Lambertz I, et al. Among authors: vandesompele j. Cell Death Differ. 2010 Apr;17(4):633-41. doi: 10.1038/cdd.2009.202. Epub 2009 Dec 18. Cell Death Differ. 2010. PMID: 20019750 Free PMC article.
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours.
Mestdagh P, Fredlund E, Pattyn F, Rihani A, Van Maerken T, Vermeulen J, Kumps C, Menten B, De Preter K, Schramm A, Schulte J, Noguera R, Schleiermacher G, Janoueix-Lerosey I, Laureys G, Powel R, Nittner D, Marine JC, Ringnér M, Speleman F, Vandesompele J. Mestdagh P, et al. Among authors: vandesompele j. Oncogene. 2010 Jun 17;29(24):3583-92. doi: 10.1038/onc.2010.106. Epub 2010 Apr 12. Oncogene. 2010. PMID: 20383195
MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia.
Mets E, Van der Meulen J, Van Peer G, Boice M, Mestdagh P, Van de Walle I, Lammens T, Goossens S, De Moerloose B, Benoit Y, Van Roy N, Clappier E, Poppe B, Vandesompele J, Wendel HG, Taghon T, Rondou P, Soulier J, Van Vlierberghe P, Speleman F. Mets E, et al. Among authors: vandesompele j. Leukemia. 2015 Apr;29(4):798-806. doi: 10.1038/leu.2014.276. Epub 2014 Sep 18. Leukemia. 2015. PMID: 25231743 Free PMC article.
EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells.
De Weer A, Van der Meulen J, Rondou P, Taghon T, Konrad TA, De Preter K, Mestdagh P, Van Maerken T, Van Roy N, Jeison M, Yaniv I, Cauwelier B, Noens L, Poirel HA, Vandenberghe P, Lambert F, De Paepe A, Sánchez MG, Odero M, Verhasselt B, Philippé J, Vandesompele J, Wieser R, Dastugue N, Van Vlierberghe P, Poppe B, Speleman F. De Weer A, et al. Among authors: vandesompele j. Br J Haematol. 2011 Aug;154(3):337-48. doi: 10.1111/j.1365-2141.2011.08737.x. Epub 2011 May 14. Br J Haematol. 2011. PMID: 21569010 Free article.
[New insights into the genetic basis of neuroblastoma].
Speleman F, De Preter K, Hoebeeck J, Van Roy N, Vandesompele J. Speleman F, et al. Among authors: vandesompele j. Verh K Acad Geneeskd Belg. 2007;69(4):167-96. Verh K Acad Geneeskd Belg. 2007. PMID: 17821957 Review. Dutch.
337 results