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Dose-dependent binding of AZD3783 to brain 5-HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369.
Varnäs K, Nyberg S, Karlsson P, Pierson ME, Kågedal M, Cselényi Z, McCarthy D, Xiao A, Zhang M, Halldin C, Farde L. Varnäs K, et al. Among authors: pierson me. Psychopharmacology (Berl). 2011 Feb;213(2-3):533-45. doi: 10.1007/s00213-011-2165-z. Epub 2011 Jan 15. Psychopharmacology (Berl). 2011. PMID: 21234549 Clinical Trial.
Quantitative analysis of [11C]AZ10419369 binding to 5-HT1B receptors in human brain.
Varnäs K, Nyberg S, Halldin C, Varrone A, Takano A, Karlsson P, Andersson J, McCarthy D, Smith M, Pierson ME, Söderström J, Farde L. Varnäs K, et al. Among authors: pierson me. J Cereb Blood Flow Metab. 2011 Jan;31(1):113-23. doi: 10.1038/jcbfm.2010.55. Epub 2010 Apr 28. J Cereb Blood Flow Metab. 2011. PMID: 20424633 Free PMC article.
[11C]AZ10419369: a selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain.
Pierson ME, Andersson J, Nyberg S, McCarthy DJ, Finnema SJ, Varnäs K, Takano A, Karlsson P, Gulyás B, Medd AM, Lee CM, Powell ME, Heys JR, Potts W, Seneca N, Mrzljak L, Farde L, Halldin C. Pierson ME, et al. Neuroimage. 2008 Jul 1;41(3):1075-85. doi: 10.1016/j.neuroimage.2008.02.063. Epub 2008 Mar 14. Neuroimage. 2008. PMID: 18434202
De novo design of a picomolar nonbasic 5-HT(1B) receptor antagonist.
Nugiel DA, Krumrine JR, Hill DC, Damewood JR Jr, Bernstein PR, Sobotka-Briner CD, Liu J, Zacco A, Pierson ME. Nugiel DA, et al. Among authors: pierson me. J Med Chem. 2010 Feb 25;53(4):1876-80. doi: 10.1021/jm901200t. J Med Chem. 2010. PMID: 20088516
31 results