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Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis.
Wilkins HM, Harris JL, Carl SM, E L, Lu J, Eva Selfridge J, Roy N, Hutfles L, Koppel S, Morris J, Burns JM, Michaelis ML, Michaelis EK, Brooks WM, Swerdlow RH. Wilkins HM, et al. Among authors: lu j. Hum Mol Genet. 2014 Dec 15;23(24):6528-41. doi: 10.1093/hmg/ddu371. Epub 2014 Jul 15. Hum Mol Genet. 2014. PMID: 25027327 Free PMC article.
Ncb5or deficiency increases fatty acid catabolism and oxidative stress.
Xu M, Wang W, Frontera JR, Neely MC, Lu J, Aires D, Hsu FF, Turk J, Swerdlow RH, Carlson SE, Zhu H. Xu M, et al. Among authors: lu j. J Biol Chem. 2011 Apr 1;286(13):11141-54. doi: 10.1074/jbc.M110.196543. Epub 2011 Feb 7. J Biol Chem. 2011. PMID: 21300801 Free PMC article.
Potentiation of dietary restriction-induced lifespan extension by polyphenols.
Aires DJ, Rockwell G, Wang T, Frontera J, Wick J, Wang W, Tonkovic-Capin M, Lu J, E L, Zhu H, Swerdlow RH. Aires DJ, et al. Among authors: lu j. Biochim Biophys Acta. 2012 Apr;1822(4):522-6. doi: 10.1016/j.bbadis.2012.01.005. Epub 2012 Jan 11. Biochim Biophys Acta. 2012. PMID: 22265987 Free PMC article.
Glycolysis-respiration relationships in a neuroblastoma cell line.
Swerdlow RH, E L, Aires D, Lu J. Swerdlow RH, et al. Among authors: lu j. Biochim Biophys Acta. 2013 Apr;1830(4):2891-8. doi: 10.1016/j.bbagen.2013.01.002. Epub 2013 Jan 10. Biochim Biophys Acta. 2013. PMID: 23313167 Free PMC article.
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