Wen D - Search Results

1

Production of a PEGylated Fab' of the anti-LINGO-1 Li33 antibody and assessment of its biochemical and functional properties in vitro and in a rat model of remyelination.

Pepinsky RB, Walus L, Shao Z, Ji B, Gu S, Sun Y, Wen D, Lee X, Wang Q, Garber E, Mi S. Pepinsky RB, et al. Among authors: wen d. Bioconjug Chem. 2011 Feb 16;22(2):200-10. doi: 10.1021/bc1002746. Epub 2011 Jan 21. Bioconjug Chem. 2011. PMID: 21254764

2

Long-acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model.

Pepinsky RB, Shapiro RI, Wang S, Chakraborty A, Gill A, Lepage DJ, Wen D, Rayhorn P, Horan GS, Taylor FR, Garber EA, Galdes A, Engber TM. Pepinsky RB, et al. Among authors: wen d. J Pharm Sci. 2002 Feb;91(2):371-87. doi: 10.1002/jps.10052. J Pharm Sci. 2002. PMID: 11835197

3

Expression, purification, and characterization of rat interferon-beta, and preparation of an N-terminally PEGylated form with improved pharmacokinetic parameters.

Arduini RM, Li Z, Rapoza A, Gronke R, Hess DM, Wen D, Miatkowski K, Coots C, Kaffashan A, Viseux N, Delaney J, Domon B, Young CN, Boynton R, Chen LL, Chen L, Betzenhauser M, Miller S, Gill A, Pepinsky RB, Hochman PS, Baker DP. Arduini RM, et al. Among authors: wen d. Protein Expr Purif. 2004 Apr;34(2):229-42. doi: 10.1016/j.pep.2003.11.004. Protein Expr Purif. 2004. PMID: 15003256

4

N-terminally PEGylated human interferon-beta-1a with improved pharmacokinetic properties and in vivo efficacy in a melanoma angiogenesis model.

Baker DP, Lin EY, Lin K, Pellegrini M, Petter RC, Chen LL, Arduini RM, Brickelmaier M, Wen D, Hess DM, Chen L, Grant D, Whitty A, Gill A, Lindner DJ, Pepinsky RB. Baker DP, et al. Among authors: wen d. Bioconjug Chem. 2006 Jan-Feb;17(1):179-88. doi: 10.1021/bc050237q. Bioconjug Chem. 2006. PMID: 16417267

5

Discovery and investigation of misincorporation of serine at asparagine positions in recombinant proteins expressed in Chinese hamster ovary cells.

Wen D, Vecchi MM, Gu S, Su L, Dolnikova J, Huang YM, Foley SF, Garber E, Pederson N, Meier W. Wen D, et al. J Biol Chem. 2009 Nov 20;284(47):32686-94. doi: 10.1074/jbc.M109.059360. Epub 2009 Sep 25. J Biol Chem. 2009. PMID: 19783658 Free PMC article.

6

Characterization of trisulfide modification in antibodies.

Gu S, Wen D, Weinreb PH, Sun Y, Zhang L, Foley SF, Kshirsagar R, Evans D, Mi S, Meier W, Pepinsky RB. Gu S, et al. Among authors: wen d. Anal Biochem. 2010 May 1;400(1):89-98. doi: 10.1016/j.ab.2010.01.019. Epub 2010 Jan 18. Anal Biochem. 2010. PMID: 20085742

7

Discovery and investigation of O-xylosylation in engineered proteins containing a (GGGGS)n linker.

Wen D, Foley SF, Hronowski XL, Gu S, Meier W. Wen D, et al. Anal Chem. 2013 May 7;85(9):4805-12. doi: 10.1021/ac400596g. Epub 2013 Apr 25. Anal Chem. 2013. PMID: 23581628

8

Resolution of disulfide heterogeneity in Nogo receptor I fusion proteins by molecular engineering.

Weinreb PH, Wen D, Qian F, Wildes CP, Garber EA, Walus L, Jung MY, Wang J, Relton JK, Amatucci J, Wang R, Porreca F, Silvian L, Meier W, Pepinsky RB, Lee DH. Weinreb PH, et al. Among authors: wen d. Biotechnol Appl Biochem. 2010 Sep;57(1):31-45. doi: 10.1042/BA20100061. Biotechnol Appl Biochem. 2010. PMID: 20815818

9

Determination of the Disulfide Structure of Murine Meteorin, a Neurotrophic Factor, by LC-MS and Electron Transfer Dissociation-High-Energy Collisional Dissociation Analysis of Proteolytic Fragments.

Wen D, Xiao Y, Vecchi MM, Gong BJ, Dolnikova J, Pepinsky RB. Wen D, et al. Anal Chem. 2017 Apr 4;89(7):4021-4030. doi: 10.1021/acs.analchem.6b04600. Epub 2017 Mar 13. Anal Chem. 2017. PMID: 28245108

10

Disulfide structure of the leucine-rich repeat C-terminal cap and C-terminal stalk region of Nogo-66 receptor.

Wen D, Wildes CP, Silvian L, Walus L, Mi S, Lee DH, Meier W, Pepinsky RB. Wen D, et al. Biochemistry. 2005 Dec 20;44(50):16491-501. doi: 10.1021/bi0517483. Biochemistry. 2005. PMID: 16342940

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