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IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway.
Lee DF, Kuo HP, Chen CT, Hsu JM, Chou CK, Wei Y, Sun HL, Li LY, Ping B, Huang WC, He X, Hung JY, Lai CC, Ding Q, Su JL, Yang JY, Sahin AA, Hortobagyi GN, Tsai FJ, Tsai CH, Hung MC. Lee DF, et al. Among authors: tsai ch, tsai fj. Cell. 2007 Aug 10;130(3):440-55. doi: 10.1016/j.cell.2007.05.058. Cell. 2007. PMID: 17693255 Free article.
ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation.
Yang JY, Zong CS, Xia W, Yamaguchi H, Ding Q, Xie X, Lang JY, Lai CC, Chang CJ, Huang WC, Huang H, Kuo HP, Lee DF, Li LY, Lien HC, Cheng X, Chang KJ, Hsiao CD, Tsai FJ, Tsai CH, Sahin AA, Muller WJ, Mills GB, Yu D, Hortobagyi GN, Hung MC. Yang JY, et al. Among authors: tsai ch, tsai fj. Nat Cell Biol. 2008 Feb;10(2):138-48. doi: 10.1038/ncb1676. Epub 2008 Jan 20. Nat Cell Biol. 2008. PMID: 18204439 Free PMC article.
Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer.
Ding Q, Huo L, Yang JY, Xia W, Wei Y, Liao Y, Chang CJ, Yang Y, Lai CC, Lee DF, Yen CJ, Chen YJ, Hsu JM, Kuo HP, Lin CY, Tsai FJ, Li LY, Tsai CH, Hung MC. Ding Q, et al. Among authors: tsai ch, tsai fj. Cancer Res. 2008 Aug 1;68(15):6109-17. doi: 10.1158/0008-5472.CAN-08-0579. Cancer Res. 2008. PMID: 18676833 Free PMC article.
AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation.
Li CW, Xia W, Lim SO, Hsu JL, Huo L, Wu Y, Li LY, Lai CC, Chang SS, Hsu YH, Sun HL, Kim J, Yamaguchi H, Lee DF, Wang H, Wang Y, Chou CK, Hsu JM, Lai YJ, LaBaff AM, Ding Q, Ko HW, Tsai FJ, Tsai CH, Hortobagyi GN, Hung MC. Li CW, et al. Among authors: tsai ch, tsai fj. Cancer Res. 2016 Mar 15;76(6):1451-62. doi: 10.1158/0008-5472.CAN-15-1941. Epub 2016 Jan 12. Cancer Res. 2016. PMID: 26759241 Free PMC article.
Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells.
Huang WC, Chen YJ, Li LY, Wei YL, Hsu SC, Tsai SL, Chiu PC, Huang WP, Wang YN, Chen CH, Chang WC, Chang WC, Chen AJ, Tsai CH, Hung MC. Huang WC, et al. Among authors: tsai sl, tsai ch. J Biol Chem. 2011 Jun 10;286(23):20558-68. doi: 10.1074/jbc.M111.240796. Epub 2011 Apr 12. J Biol Chem. 2011. PMID: 21487020 Free PMC article.
2,233 results