Bullock AN - Search Results

1

Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing.

Fedorov O, Huber K, Eisenreich A, Filippakopoulos P, King O, Bullock AN, Szklarczyk D, Jensen LJ, Fabbro D, Trappe J, Rauch U, Bracher F, Knapp S. Fedorov O, et al. Among authors: bullock an. Chem Biol. 2011 Jan 28;18(1):67-76. doi: 10.1016/j.chembiol.2010.11.009. Chem Biol. 2011. PMID: 21276940 Free PMC article.

2

Structure and substrate specificity of the Pim-1 kinase.

Bullock AN, Debreczeni J, Amos AL, Knapp S, Turk BE. Bullock AN, et al. J Biol Chem. 2005 Dec 16;280(50):41675-82. doi: 10.1074/jbc.M510711200. Epub 2005 Oct 13. J Biol Chem. 2005. PMID: 16227208 Free article.

3

Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.

Bullock AN, Debreczeni JE, Fedorov OY, Nelson A, Marsden BD, Knapp S. Bullock AN, et al. J Med Chem. 2005 Dec 1;48(24):7604-14. doi: 10.1021/jm0504858. J Med Chem. 2005. PMID: 16302800

4

Ruthenium half-sandwich complexes bound to protein kinase Pim-1.

Debreczeni JE, Bullock AN, Atilla GE, Williams DS, Bregman H, Knapp S, Meggers E. Debreczeni JE, et al. Among authors: bullock an. Angew Chem Int Ed Engl. 2006 Feb 27;45(10):1580-5. doi: 10.1002/anie.200503468. Angew Chem Int Ed Engl. 2006. PMID: 16381041 No abstract available.

5

Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.

Bullock AN, Debreczeni JE, Edwards AM, Sundström M, Knapp S. Bullock AN, et al. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7637-42. doi: 10.1073/pnas.0601638103. Epub 2006 May 4. Proc Natl Acad Sci U S A. 2006. PMID: 16675548 Free PMC article.

6

Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity.

Pogacic V, Bullock AN, Fedorov O, Filippakopoulos P, Gasser C, Biondi A, Meyer-Monard S, Knapp S, Schwaller J. Pogacic V, et al. Among authors: bullock an. Cancer Res. 2007 Jul 15;67(14):6916-24. doi: 10.1158/0008-5472.CAN-07-0320. Cancer Res. 2007. PMID: 17638903

7

Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation.

Bullock AN, Rodriguez MC, Debreczeni JE, Songyang Z, Knapp S. Bullock AN, et al. Structure. 2007 Nov;15(11):1493-504. doi: 10.1016/j.str.2007.09.016. Structure. 2007. PMID: 17997974 Free PMC article.

8

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Fedorov O, Marsden B, Pogacic V, Rellos P, Müller S, Bullock AN, Schwaller J, Sundström M, Knapp S. Fedorov O, et al. Among authors: bullock an. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20523-8. doi: 10.1073/pnas.0708800104. Epub 2007 Dec 11. Proc Natl Acad Sci U S A. 2007. PMID: 18077363 Free PMC article.

9

The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.

Baumli S, Lolli G, Lowe ED, Troiani S, Rusconi L, Bullock AN, Debreczeni JE, Knapp S, Johnson LN. Baumli S, et al. Among authors: bullock an. EMBO J. 2008 Jul 9;27(13):1907-18. doi: 10.1038/emboj.2008.121. Epub 2008 Jun 19. EMBO J. 2008. PMID: 18566585 Free PMC article.

10

Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation.

Bullock AN, Das S, Debreczeni JE, Rellos P, Fedorov O, Niesen FH, Guo K, Papagrigoriou E, Amos AL, Cho S, Turk BE, Ghosh G, Knapp S. Bullock AN, et al. Structure. 2009 Mar 11;17(3):352-62. doi: 10.1016/j.str.2008.12.023. Structure. 2009. PMID: 19278650 Free PMC article.

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