Jenh CH - Search Results

1

II. SAR studies of pyridyl-piperazinyl-piperidine derivatives as CXCR3 chemokine antagonists.

Shao Y, Anilkumar GN, Carroll CD, Dong G, Hall JW 3rd, Hobbs DW, Jiang Y, Jenh CH, Kim SH, Kozlowski JA, McGuinness BF, Rosenblum SB, Schulman I, Shih NY, Shu Y, Wong MK, Yu W, Zawacki LG, Zeng Q. Shao Y, et al. Among authors: jenh ch. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1527-31. doi: 10.1016/j.bmcl.2010.12.114. Epub 2010 Dec 28. Bioorg Med Chem Lett. 2011. PMID: 21277198

2

IV. Discovery of CXCR3 antagonists substituted with heterocycles as amide surrogates: improved PK, hERG and metabolic profiles.

Nair AG, Wong MK, Shu Y, Jiang Y, Jenh CH, Kim SH, Yang DY, Zeng Q, Shao Y, Zawacki LG, Duo J, McGuinness BF, Carroll CD, Hobbs DW, Shih NY, Rosenblum SB, Kozlowski JA. Nair AG, et al. Among authors: jenh ch. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1085-8. doi: 10.1016/j.bmcl.2014.01.009. Epub 2014 Jan 11. Bioorg Med Chem Lett. 2014. PMID: 24486132

3

Novel CXCR3 antagonists with a piperazinyl-piperidine core.

McGuinness BF, Carroll CD, Zawacki LG, Dong G, Yang C, Hobbs DW, Jacob-Samuel B, Hall JW 3rd, Jenh CH, Kozlowski JA, Anilkumar GN, Rosenblum SB. McGuinness BF, et al. Among authors: jenh ch. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5205-8. doi: 10.1016/j.bmcl.2009.07.020. Epub 2009 Jul 9. Bioorg Med Chem Lett. 2009. PMID: 19647429

4

III. Identification of novel CXCR3 chemokine receptor antagonists with a pyrazinyl-piperazinyl-piperidine scaffold.

Kim SH, Anilkumar GN, Zawacki LG, Zeng Q, Yang DY, Shao Y, Dong G, Xu X, Yu W, Jiang Y, Jenh CH, Hall JW 3rd, Carroll CD, Hobbs DW, Baldwin JJ, McGuinness BF, Rosenblum SB, Kozlowski JA, Shankar BB, Shih NY. Kim SH, et al. Among authors: jenh ch. Bioorg Med Chem Lett. 2011 Dec 1;21(23):6982-6. doi: 10.1016/j.bmcl.2011.09.120. Epub 2011 Oct 5. Bioorg Med Chem Lett. 2011. PMID: 22018463

5

A selective and potent CXCR3 antagonist SCH 546738 attenuates the development of autoimmune diseases and delays graft rejection.

Jenh CH, Cox MA, Cui L, Reich EP, Sullivan L, Chen SC, Kinsley D, Qian S, Kim SH, Rosenblum S, Kozlowski J, Fine JS, Zavodny PJ, Lundell D. Jenh CH, et al. BMC Immunol. 2012 Jan 10;13:2. doi: 10.1186/1471-2172-13-2. BMC Immunol. 2012. PMID: 22233170 Free PMC article.

6

Targeting CXCR3 reduces ligand-induced T-cell activation but not development of lung allergic responses.

Shin YS, Takeda K, Ohnishi H, Jia Y, Shiraishi Y, Cox ML, Fine JS, Rosenblum S, Lundel D, Jenh CH, Manfra DJ, Gelfand EW. Shin YS, et al. Among authors: jenh ch. Ann Allergy Asthma Immunol. 2011 Aug;107(2):145-53. doi: 10.1016/j.anai.2011.04.013. Epub 2011 Jun 12. Ann Allergy Asthma Immunol. 2011. PMID: 21802023

7

Condensed aromatic peptide family of microbial metabolites, inhibitors of CD28-CD80 interactions.

Hegde VR, Puar MS, Dai P, Patel M, Gullo VP, Chan TM, Silver J, Pramanik BN, Jenh CH. Hegde VR, et al. Among authors: jenh ch. Bioorg Med Chem Lett. 2003 Feb 10;13(3):573-5. doi: 10.1016/s0960-894x(02)00919-8. Bioorg Med Chem Lett. 2003. PMID: 12565974

8

Human B cell-attracting chemokine 1 (BCA-1; CXCL13) is an agonist for the human CXCR3 receptor.

Jenh CH, Cox MA, Hipkin W, Lu T, Pugliese-Sivo C, Gonsiorek W, Chou CC, Narula SK, Zavodny PJ. Jenh CH, et al. Cytokine. 2001 Aug 7;15(3):113-21. doi: 10.1006/cyto.2001.0923. Cytokine. 2001. PMID: 11554781

9

Cutting edge: species specificity of the CC chemokine 6Ckine signaling through the CXC chemokine receptor CXCR3: human 6Ckine is not a ligand for the human or mouse CXCR3 receptors.

Jenh CH, Cox MA, Kaminski H, Zhang M, Byrnes H, Fine J, Lundell D, Chou CC, Narula SK, Zavodny PJ. Jenh CH, et al. J Immunol. 1999 Apr 1;162(7):3765-9. J Immunol. 1999. PMID: 10201891

10

A highly sensitive and specific assay using a novel human growth hormone cDNA reporter gene regulated by the human interleukin-4 inducible germline epsilon transcript promoter.

Jenh CH, Cox MA, Lundell D, Narula SK, Zavodny PJ. Jenh CH, et al. J Immunol Methods. 1998 Aug 1;217(1-2):87-95. doi: 10.1016/s0022-1759(98)00095-7. J Immunol Methods. 1998. PMID: 9776578

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