Datti A - Search Results

1

Small molecule kinase inhibitor screen identifies polo-like kinase 1 as a target for neuroblastoma tumor-initiating cells.

Grinshtein N, Datti A, Fujitani M, Uehling D, Prakesch M, Isaac M, Irwin MS, Wrana JL, Al-Awar R, Kaplan DR. Grinshtein N, et al. Among authors: datti a. Cancer Res. 2011 Feb 15;71(4):1385-95. doi: 10.1158/0008-5472.CAN-10-2484. Epub 2011 Feb 8. Cancer Res. 2011. PMID: 21303981

2

A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis.

Mawji IA, Simpson CD, Gronda M, Williams MA, Hurren R, Henderson CJ, Datti A, Wrana JL, Schimmer AD. Mawji IA, et al. Among authors: datti a. Cancer Res. 2007 Sep 1;67(17):8307-15. doi: 10.1158/0008-5472.CAN-07-1687. Cancer Res. 2007. PMID: 17804746 Free article.

3

Complex N-glycan and metabolic control in tumor cells.

Mendelsohn R, Cheung P, Berger L, Partridge E, Lau K, Datti A, Pawling J, Dennis JW. Mendelsohn R, et al. Among authors: datti a. Cancer Res. 2007 Oct 15;67(20):9771-80. doi: 10.1158/0008-5472.CAN-06-4580. Cancer Res. 2007. PMID: 17942907

4

A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization.

Xu GW, Mawji IA, Macrae CJ, Koch CA, Datti A, Wrana JL, Dennis JW, Schimmer AD. Xu GW, et al. Among authors: datti a. Apoptosis. 2008 Mar;13(3):413-22. doi: 10.1007/s10495-007-0175-4. Apoptosis. 2008. PMID: 18181020

5

Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function.

Beheshti Zavareh R, Lau KS, Hurren R, Datti A, Ashline DJ, Gronda M, Cheung P, Simpson CD, Liu W, Wasylishen AR, Boutros PC, Shi H, Vengopal A, Jurisica I, Penn LZ, Reinhold VN, Ezzat S, Wrana J, Rose DR, Schachter H, Dennis JW, Schimmer AD. Beheshti Zavareh R, et al. Among authors: datti a. Cancer Res. 2008 Aug 15;68(16):6688-97. doi: 10.1158/0008-5472.CAN-07-6833. Cancer Res. 2008. PMID: 18701493

6

High-throughput screening identifies cardiac glycosides as potent inhibitors of human tissue kallikrein expression: implications for cancer therapies.

Prassas I, Paliouras M, Datti A, Diamandis EP. Prassas I, et al. Among authors: datti a. Clin Cancer Res. 2008 Sep 15;14(18):5778-84. doi: 10.1158/1078-0432.CCR-08-0706. Clin Cancer Res. 2008. PMID: 18794087

7

Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation.

Simpson CD, Mawji IA, Anyiwe K, Williams MA, Wang X, Venugopal AL, Gronda M, Hurren R, Cheng S, Serra S, Beheshti Zavareh R, Datti A, Wrana JL, Ezzat S, Schimmer AD. Simpson CD, et al. Among authors: datti a. Cancer Res. 2009 Apr 1;69(7):2739-47. doi: 10.1158/0008-5472.CAN-08-2530. Epub 2009 Mar 17. Cancer Res. 2009. PMID: 19293189

8

Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells.

Eberhard Y, McDermott SP, Wang X, Gronda M, Venugopal A, Wood TE, Hurren R, Datti A, Batey RA, Wrana J, Antholine WE, Dick JE, Schimmer AD. Eberhard Y, et al. Among authors: datti a. Blood. 2009 Oct 1;114(14):3064-73. doi: 10.1182/blood-2009-03-209965. Epub 2009 Jul 9. Blood. 2009. PMID: 19589922 Free article.

9

Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway.

Miller BW, Lau G, Grouios C, Mollica E, Barrios-Rodiles M, Liu Y, Datti A, Morris Q, Wrana JL, Attisano L. Miller BW, et al. Among authors: datti a. Mol Syst Biol. 2009;5:315. doi: 10.1038/msb.2009.72. Epub 2009 Oct 13. Mol Syst Biol. 2009. PMID: 19888210 Free PMC article.

10

Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming.

Samavarchi-Tehrani P, Golipour A, David L, Sung HK, Beyer TA, Datti A, Woltjen K, Nagy A, Wrana JL. Samavarchi-Tehrani P, et al. Among authors: datti a. Cell Stem Cell. 2010 Jul 2;7(1):64-77. doi: 10.1016/j.stem.2010.04.015. Epub 2010 Jun 17. Cell Stem Cell. 2010. PMID: 20621051 Free article.

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