Khanfar MA - Search Results

1

Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors.

Hassan HM, Elnagar AY, Khanfar MA, Sallam AA, Mohammed R, Shaala LA, Youssef DT, Hifnawy MS, El Sayed KA. Hassan HM, et al. Among authors: khanfar ma. Eur J Med Chem. 2011 Apr;46(4):1122-30. doi: 10.1016/j.ejmech.2011.01.028. Epub 2011 Jan 28. Eur J Med Chem. 2011. PMID: 21334794

2

Latrunculin A and its C-17-O-carbamates inhibit prostate tumor cell invasion and HIF-1 activation in breast tumor cells.

Sayed KA, Khanfar MA, Shallal HM, Muralidharan A, Awate B, Youssef DT, Liu Y, Zhou YD, Nagle DG, Shah G. Sayed KA, et al. Among authors: khanfar ma. J Nat Prod. 2008 Mar;71(3):396-402. doi: 10.1021/np070587w. Epub 2008 Feb 26. J Nat Prod. 2008. PMID: 18298079 Free PMC article.

3

Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products.

Mudit M, Khanfar M, Muralidharan A, Thomas S, Shah GV, van Soest RW, El Sayed KA. Mudit M, et al. Bioorg Med Chem. 2009 Feb 15;17(4):1731-8. doi: 10.1016/j.bmc.2008.12.053. Epub 2008 Dec 29. Bioorg Med Chem. 2009. PMID: 19195897

4

Identification of a small molecule class to enhance cell-cell adhesion and attenuate prostate tumor growth and metastasis.

Shah GV, Muralidharan A, Thomas S, Gokulgandhi M, Mudit M, Khanfar M, El Sayed K. Shah GV, et al. Mol Cancer Ther. 2009 Mar;8(3):509-20. doi: 10.1158/1535-7163.MCT-08-0693. Epub 2009 Mar 10. Mol Cancer Ther. 2009. PMID: 19276166 Free PMC article.

5

The marine natural-derived inhibitors of glycogen synthase kinase-3beta phenylmethylene hydantoins: In vitro and in vivo activities and pharmacophore modeling.

Khanfar MA, Asal BA, Mudit M, Kaddoumi A, El Sayed KA. Khanfar MA, et al. Bioorg Med Chem. 2009 Aug 15;17(16):6032-9. doi: 10.1016/j.bmc.2009.06.054. Epub 2009 Jun 27. Bioorg Med Chem. 2009. PMID: 19616957 Free PMC article.

6

Rational design and semisynthesis of betulinic acid analogues as potent topoisomerase inhibitors.

Bar FM, Khanfar MA, Elnagar AY, Liu H, Zaghloul AM, Badria FA, Sylvester PW, Ahmad KF, Raisch KP, El Sayed KA. Bar FM, et al. Among authors: khanfar ma. J Nat Prod. 2009 Sep;72(9):1643-50. doi: 10.1021/np900312u. J Nat Prod. 2009. PMID: 19691293

7

Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors.

Abdel Bar FM, Khanfar MA, Elnagar AY, Badria FA, Zaghloul AM, Ahmad KF, Sylvester PW, El Sayed KA. Abdel Bar FM, et al. Among authors: khanfar ma. Bioorg Med Chem. 2010 Jan 15;18(2):496-507. doi: 10.1016/j.bmc.2009.12.019. Epub 2009 Dec 11. Bioorg Med Chem. 2010. PMID: 20034800

8

Semisynthetic latrunculin derivatives as inhibitors of metastatic breast cancer: biological evaluations, preliminary structure-activity relationship and molecular modeling studies.

Khanfar MA, Youssef DT, El Sayed KA. Khanfar MA, et al. ChemMedChem. 2010 Feb 1;5(2):274-85. doi: 10.1002/cmdc.200900430. ChemMedChem. 2010. PMID: 20043312 Free PMC article.

9

Pachycladins A-E, prostate cancer invasion and migration inhibitory Eunicellin-based diterpenoids from the red sea soft coral Cladiella pachyclados.

Hassan HM, Khanfar MA, Elnagar AY, Mohammed R, Shaala LA, Youssef DT, Hifnawy MS, El Sayed KA. Hassan HM, et al. Among authors: khanfar ma. J Nat Prod. 2010 May 28;73(5):848-53. doi: 10.1021/np900787p. J Nat Prod. 2010. PMID: 20420415

10

3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches.

Khanfar MA, Youssef DT, El Sayed KA. Khanfar MA, et al. Eur J Med Chem. 2010 Sep;45(9):3662-8. doi: 10.1016/j.ejmech.2010.05.012. Epub 2010 May 12. Eur J Med Chem. 2010. PMID: 20684858 Free PMC article.

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