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Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix.
Cochemé HM, Quin C, McQuaker SJ, Cabreiro F, Logan A, Prime TA, Abakumova I, Patel JV, Fearnley IM, James AM, Porteous CM, Smith RA, Saeed S, Carré JE, Singer M, Gems D, Hartley RC, Partridge L, Murphy MP. Cochemé HM, et al. Among authors: porteous cm. Cell Metab. 2011 Mar 2;13(3):340-50. doi: 10.1016/j.cmet.2011.02.003. Cell Metab. 2011. PMID: 21356523 Free PMC article.
Assessing the Mitochondrial Membrane Potential in Cells and In Vivo using Targeted Click Chemistry and Mass Spectrometry.
Logan A, Pell VR, Shaffer KJ, Evans C, Stanley NJ, Robb EL, Prime TA, Chouchani ET, Cochemé HM, Fearnley IM, Vidoni S, James AM, Porteous CM, Partridge L, Krieg T, Smith RA, Murphy MP. Logan A, et al. Among authors: porteous cm. Cell Metab. 2016 Feb 9;23(2):379-85. doi: 10.1016/j.cmet.2015.11.014. Epub 2015 Dec 17. Cell Metab. 2016. PMID: 26712463 Free PMC article.
Delivery of bioactive molecules to mitochondria in vivo.
Smith RA, Porteous CM, Gane AM, Murphy MP. Smith RA, et al. Among authors: porteous cm. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5407-12. doi: 10.1073/pnas.0931245100. Epub 2003 Apr 15. Proc Natl Acad Sci U S A. 2003. PMID: 12697897 Free PMC article.
Accumulation of lipophilic dications by mitochondria and cells.
Ross MF, Da Ros T, Blaikie FH, Prime TA, Porteous CM, Severina II, Skulachev VP, Kjaergaard HG, Smith RA, Murphy MP. Ross MF, et al. Among authors: porteous cm. Biochem J. 2006 Nov 15;400(1):199-208. doi: 10.1042/BJ20060919. Biochem J. 2006. PMID: 16948637 Free PMC article.
Mitochondrial targeting of quinones: therapeutic implications.
Cochemé HM, Kelso GF, James AM, Ross MF, Trnka J, Mahendiran T, Asin-Cayuela J, Blaikie FH, Manas AR, Porteous CM, Adlam VJ, Smith RA, Murphy MP. Cochemé HM, et al. Among authors: porteous cm. Mitochondrion. 2007 Jun;7 Suppl:S94-102. doi: 10.1016/j.mito.2007.02.007. Epub 2007 Mar 16. Mitochondrion. 2007. PMID: 17449335 Review.
Mitochondria-targeted antioxidants in the treatment of disease.
Smith RA, Adlam VJ, Blaikie FH, Manas AR, Porteous CM, James AM, Ross MF, Logan A, Cochemé HM, Trnka J, Prime TA, Abakumova I, Jones BA, Filipovska A, Murphy MP. Smith RA, et al. Among authors: porteous cm. Ann N Y Acad Sci. 2008 Dec;1147:105-11. doi: 10.1196/annals.1427.003. Ann N Y Acad Sci. 2008. PMID: 19076435 Review.
A mitochondria-targeted macrocyclic Mn(II) superoxide dismutase mimetic.
Kelso GF, Maroz A, Cochemé HM, Logan A, Prime TA, Peskin AV, Winterbourn CC, James AM, Ross MF, Brooker S, Porteous CM, Anderson RF, Murphy MP, Smith RA. Kelso GF, et al. Among authors: porteous cm. Chem Biol. 2012 Oct 26;19(10):1237-46. doi: 10.1016/j.chembiol.2012.08.005. Chem Biol. 2012. PMID: 23102218
36 results