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Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus.
Lande R, Ganguly D, Facchinetti V, Frasca L, Conrad C, Gregorio J, Meller S, Chamilos G, Sebasigari R, Riccieri V, Bassett R, Amuro H, Fukuhara S, Ito T, Liu YJ, Gilliet M. Lande R, et al. Among authors: amuro h. Sci Transl Med. 2011 Mar 9;3(73):73ra19. doi: 10.1126/scitranslmed.3001180. Sci Transl Med. 2011. PMID: 21389263 Free PMC article.
Inhibitor of IkappaB kinase activity, BAY 11-7082, interferes with interferon regulatory factor 7 nuclear translocation and type I interferon production by plasmacytoid dendritic cells.
Miyamoto R, Ito T, Nomura S, Amakawa R, Amuro H, Katashiba Y, Ogata M, Murakami N, Shimamoto K, Yamazaki C, Hoshino K, Kaisho T, Fukuhara S. Miyamoto R, et al. Among authors: amuro h. Arthritis Res Ther. 2010;12(3):R87. doi: 10.1186/ar3014. Epub 2010 May 14. Arthritis Res Ther. 2010. PMID: 20470398 Free PMC article.
Mycophenolic acid, the active form of mycophenolate mofetil, interferes with IRF7 nuclear translocation and type I IFN production by plasmacytoid dendritic cells.
Shigesaka M, Ito T, Inaba M, Imai K, Yamanaka H, Azuma Y, Tanaka A, Amuro H, Nishizawa T, Son Y, Satake A, Ozaki Y, Nomura S. Shigesaka M, et al. Among authors: amuro h. Arthritis Res Ther. 2020 Nov 9;22(1):264. doi: 10.1186/s13075-020-02356-z. Arthritis Res Ther. 2020. PMID: 33168076 Free PMC article.
Decrease of blood dendritic cells and increase of tissue-infiltrating dendritic cells are involved in the induction of Sjögren's syndrome but not in the maintenance.
Ozaki Y, Ito T, Son Y, Amuro H, Shimamoto K, Sugimoto H, Katashiba Y, Ogata M, Miyamoto R, Murakami N, Amakawa R, Fukuhara S. Ozaki Y, et al. Among authors: amuro h. Clin Exp Immunol. 2010 Mar;159(3):315-26. doi: 10.1111/j.1365-2249.2009.04071.x. Epub 2009 Dec 14. Clin Exp Immunol. 2010. PMID: 20015272 Free PMC article.
45 results