Gao T - Search Results

1

mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.

Gulhati P, Bowen KA, Liu J, Stevens PD, Rychahou PG, Chen M, Lee EY, Weiss HL, O'Connor KL, Gao T, Evers BM. Gulhati P, et al. Among authors: gao t. Cancer Res. 2011 May 1;71(9):3246-56. doi: 10.1158/0008-5472.CAN-10-4058. Epub 2011 Mar 23. Cancer Res. 2011. PMID: 21430067 Free PMC article.

2

Protein kinase Cdelta negatively regulates hedgehog signaling by inhibition of Gli1 activity.

Cai Q, Li J, Gao T, Xie J, Evers BM. Cai Q, et al. Among authors: gao t. J Biol Chem. 2009 Jan 23;284(4):2150-8. doi: 10.1074/jbc.M803235200. Epub 2008 Nov 17. J Biol Chem. 2009. PMID: 19015273 Free PMC article.

3

Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis.

Liu J, Weiss HL, Rychahou P, Jackson LN, Evers BM, Gao T. Liu J, et al. Among authors: gao t. Oncogene. 2009 Feb 19;28(7):994-1004. doi: 10.1038/onc.2008.450. Epub 2008 Dec 15. Oncogene. 2009. PMID: 19079341 Free PMC article.

4

Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling.

Johnson SM, Gulhati P, Arrieta I, Wang X, Uchida T, Gao T, Evers BM. Johnson SM, et al. Among authors: gao t. Anticancer Res. 2009 Aug;29(8):3185-90. Anticancer Res. 2009. PMID: 19661333 Free PMC article.

5

beta-TrCP-mediated ubiquitination and degradation of PHLPP1 are negatively regulated by Akt.

Li X, Liu J, Gao T. Li X, et al. Among authors: gao t. Mol Cell Biol. 2009 Dec;29(23):6192-205. doi: 10.1128/MCB.00681-09. Epub 2009 Sep 21. Mol Cell Biol. 2009. PMID: 19797085 Free PMC article.

6

Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer.

Gulhati P, Cai Q, Li J, Liu J, Rychahou PG, Qiu S, Lee EY, Silva SR, Bowen KA, Gao T, Evers BM. Gulhati P, et al. Among authors: gao t. Clin Cancer Res. 2009 Dec 1;15(23):7207-16. doi: 10.1158/1078-0432.CCR-09-1249. Epub 2009 Nov 24. Clin Cancer Res. 2009. PMID: 19934294 Free PMC article.

7

Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1.

Larson Y, Liu J, Stevens PD, Li X, Li J, Evers BM, Gao T. Larson Y, et al. Among authors: gao t. J Biol Chem. 2010 Aug 6;285(32):24987-98. doi: 10.1074/jbc.M109.096917. Epub 2010 Jun 8. J Biol Chem. 2010. PMID: 20530489 Free PMC article.

8

mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.

Liu J, Stevens PD, Gao T. Liu J, et al. Among authors: gao t. J Biol Chem. 2011 Feb 25;286(8):6510-20. doi: 10.1074/jbc.M110.183087. Epub 2010 Dec 22. J Biol Chem. 2011. PMID: 21177869 Free PMC article.

9

mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON.

Li J, Liu J, Song J, Wang X, Weiss HL, Townsend CM Jr, Gao T, Evers BM. Li J, et al. Among authors: gao t. Am J Physiol Cell Physiol. 2011 Jul;301(1):C213-26. doi: 10.1152/ajpcell.00067.2011. Epub 2011 Apr 20. Am J Physiol Cell Physiol. 2011. PMID: 21508335 Free PMC article.

10

Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt.

Li X, Yang H, Liu J, Schmidt MD, Gao T. Li X, et al. Among authors: gao t. EMBO Rep. 2011 Jun 24;12(8):818-24. doi: 10.1038/embor.2011.106. EMBO Rep. 2011. PMID: 21701506 Free PMC article.

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