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Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis.
Yang DS, Stavrides P, Mohan PS, Kaushik S, Kumar A, Ohno M, Schmidt SD, Wesson DW, Bandyopadhyay U, Jiang Y, Pawlik M, Peterhoff CM, Yang AJ, Wilson DA, St George-Hyslop P, Westaway D, Mathews PM, Levy E, Cuervo AM, Nixon RA. Yang DS, et al. Among authors: cuervo am. Autophagy. 2011 Jul;7(7):788-9. doi: 10.4161/auto.7.7.15596. Epub 2011 Jul 1. Autophagy. 2011. PMID: 21464620 Free PMC article.
Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease.
Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH, Mohan PS, Mercken M, Farmery MR, Tjernberg LO, Jiang Y, Duff K, Uchiyama Y, Näslund J, Mathews PM, Cataldo AM, Nixon RA. Yu WH, et al. Among authors: cuervo am. J Cell Biol. 2005 Oct 10;171(1):87-98. doi: 10.1083/jcb.200505082. Epub 2005 Oct 3. J Cell Biol. 2005. PMID: 16203860 Free PMC article.
Oxidative stress and autophagy.
Kiffin R, Bandyopadhyay U, Cuervo AM. Kiffin R, et al. Among authors: cuervo am. Antioxid Redox Signal. 2006 Jan-Feb;8(1-2):152-62. doi: 10.1089/ars.2006.8.152. Antioxid Redox Signal. 2006. PMID: 16487049 Review.
Consequences of the selective blockage of chaperone-mediated autophagy.
Massey AC, Kaushik S, Sovak G, Kiffin R, Cuervo AM. Massey AC, et al. Among authors: cuervo am. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5805-10. doi: 10.1073/pnas.0507436103. Epub 2006 Apr 3. Proc Natl Acad Sci U S A. 2006. PMID: 16585521 Free PMC article.
Lysosomal chat maintains the balance.
Massey AC, Kaushik S, Cuervo AM. Massey AC, et al. Among authors: cuervo am. Autophagy. 2006 Oct-Dec;2(4):325-7. doi: 10.4161/auto.3090. Epub 2006 Oct 13. Autophagy. 2006. PMID: 16874078 Review.
298 results