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167 results

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Page 1
The AlzMatch Pilot Study - Feasibility of Remote Blood Collection of Plasma Biomarkers for Preclinical Alzheimer's Disease Trials.
Walter S, Langford O, Jimenez-Maggiora GA, Abdel-Latif S, Rissman RA, Grill JD, Karlawish J, Atri A, Bruschi S, Hussen K, Donohue MC, Marshall GA, Jicha G, Racke M, Turner RS, van Dyck CH, Venkatesh V, Yarasheski KE, Sperling R, Cummings J, Aisen PS, Raman R. Walter S, et al. Among authors: yarasheski ke. J Prev Alzheimers Dis. 2024;11(5):1435-1444. doi: 10.14283/jpad.2024.101. J Prev Alzheimers Dis. 2024. PMID: 39350391 Free PMC article.
PrecivityAD2™ Blood Test: Analytical Validation of an LC-MS/MS Assay for Quantifying Plasma Phospho-tau217 and Non-Phospho-tau217 Peptide Concentrations That Are Used with Plasma Amyloid-β42/40 in a Multianalyte Assay with Algorithmic Analysis for Detecting Brain Amyloid Pathology.
Eastwood SM, Meyer MR, Kirmess KM, Wente-Roth TL, Irvin F, Holubasch MS, Verghese PB, West T, Braunstein JB, Yarasheski KE, Contois JH. Eastwood SM, et al. Among authors: yarasheski ke. Diagnostics (Basel). 2024 Aug 10;14(16):1739. doi: 10.3390/diagnostics14161739. Diagnostics (Basel). 2024. PMID: 39202226 Free PMC article.
Unexpected Low Rate of Amyloid-β Pathology in Multiple Sclerosis Patients.
Brier MR, Schindler SE, Salter A, Perantie D, Shelley N, Judge B, Keefe S, Kirmess KM, Verghese PB, Yarasheski KE, Venkatesh V, Raji CA, Gordon BA, Bateman RJ, Morris JC, Naismith RT, Holtzman DM, Benzinger TLS, Cross AH. Brier MR, et al. Among authors: yarasheski ke. Ann Neurol. 2024 Sep;96(3):453-459. doi: 10.1002/ana.27027. Epub 2024 Jul 4. Ann Neurol. 2024. PMID: 38963256
Protocol for a seamless phase 2A-phase 2B randomized double-blind placebo-controlled trial to evaluate the safety and efficacy of benfotiamine in patients with early Alzheimer's disease (BenfoTeam).
Feldman HH, Luchsinger JA, Léger GC, Taylor C, Jacobs DM, Salmon DP, Edland SD, Messer K, Revta C, Flowers SA, Jones KS, Koulman A, Yarasheski KE, Verghese PB, Venkatesh V, Zetterberg H, Durant J, Lupo JL, Gibson GE; ADCS BenfoTeam Study Group. Feldman HH, et al. Among authors: yarasheski ke. PLoS One. 2024 May 29;19(5):e0302998. doi: 10.1371/journal.pone.0302998. eCollection 2024. PLoS One. 2024. PMID: 38809849 Free PMC article. Clinical Trial.
Sensitivity of the African neuropsychology battery memory subtests and learning slopes in discriminating APOE 4 and amyloid pathology in adult individuals in the Democratic Republic of Congo.
Ikanga J, Patrick SD, Schwinne M, Patel SS, Epenge E, Gikelekele G, Tshengele N, Kavugho I, Mampunza S, Yarasheski KE, Teunissen CE, Stringer A, Levey A, Rojas JC, Chan B, Lario Lago A, Kramer JH, Boxer AL, Jeromin A, Alonso A, Spencer RJ. Ikanga J, et al. Among authors: yarasheski ke. Front Neurol. 2024 Mar 27;15:1320727. doi: 10.3389/fneur.2024.1320727. eCollection 2024. Front Neurol. 2024. PMID: 38601333 Free PMC article.
Clinical validation of the PrecivityAD2 blood test: A mass spectrometry-based test with algorithm combining %p-tau217 and Aβ42/40 ratio to identify presence of brain amyloid.
Meyer MR, Kirmess KM, Eastwood S, Wente-Roth TL, Irvin F, Holubasch MS, Venkatesh V, Fogelman I, Monane M, Hanna L, Rabinovici GD, Siegel BA, Whitmer RA, Apgar C, Bateman RJ, Holtzman DM, Irizarry M, Verbel D, Sachdev P, Ito S, Contois J, Yarasheski KE, Braunstein JB, Verghese PB, West T. Meyer MR, et al. Among authors: yarasheski ke. Alzheimers Dement. 2024 May;20(5):3179-3192. doi: 10.1002/alz.13764. Epub 2024 Mar 16. Alzheimers Dement. 2024. PMID: 38491912 Free PMC article.
The Association of Alzheimer's Disease-Related Blood-Based Biomarkers with Cognitive Screening Test Performance in the Congolese Population in Kinshasa.
Schwinne M, Alonso A, Roberts BR, Hickle S, Verberk IMW, Epenge E, Gikelekele G, Tsengele N, Kavugho I, Mampunza S, Yarasheski KE, Teunissen CE, Stringer A, Levey A, Ikanga J. Schwinne M, et al. Among authors: yarasheski ke. J Alzheimers Dis. 2024;97(3):1353-1363. doi: 10.3233/JAD-230976. J Alzheimers Dis. 2024. PMID: 38306056
Associations of sleep duration and daytime sleepiness with plasma amyloid beta and cognitive performance in cognitively unimpaired, middle-aged and older African Americans.
Cook JD, Malik A, Plante DT, Norton D, Langhough Koscik R, Du L, Bendlin BB, Kirmess KM, Holubasch MS, Meyer MR, Venkatesh V, West T, Verghese PB, Yarasheski KE, Thomas KV, Carlsson CM, Asthana S, Johnson SC, Gleason CE, Zuelsdorff M. Cook JD, et al. Among authors: yarasheski ke. Sleep. 2024 Jan 11;47(1):zsad302. doi: 10.1093/sleep/zsad302. Sleep. 2024. PMID: 38011629 Free PMC article.
Association of plasma biomarkers with cognitive function in persons with dementia and cognitively healthy in the Democratic Republic of Congo.
Ikanga J, Patel SS, Roberts BR, Schwinne M, Hickle S, Verberk IMW, Epenge E, Gikelekele G, Tshengele N, Kavugho I, Mampunza S, Yarasheski KE, Teunissen CE, Stringer A, Levey A, Alonso A. Ikanga J, et al. Among authors: yarasheski ke. Alzheimers Dement (Amst). 2023 Nov 8;15(4):e12496. doi: 10.1002/dad2.12496. eCollection 2023 Oct-Dec. Alzheimers Dement (Amst). 2023. PMID: 37954546 Free PMC article.
Plasma Aβ42/Aβ40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease.
Rissman RA, Langford O, Raman R, Donohue MC, Abdel-Latif S, Meyer MR, Wente-Roth T, Kirmess KM, Ngolab J, Winston CN, Jimenez-Maggiora G, Rafii MS, Sachdev P, West T, Yarasheski KE, Braunstein JB, Irizarry M, Johnson KA, Aisen PS, Sperling RA; AHEAD 3-45 Study team. Rissman RA, et al. Among authors: yarasheski ke. Alzheimers Dement. 2024 Feb;20(2):1214-1224. doi: 10.1002/alz.13542. Epub 2023 Nov 6. Alzheimers Dement. 2024. PMID: 37932961 Free PMC article.
167 results