Thierbach R - Search Results

1

Inhibition of alanine aminotransferase in silico and in vivo promotes mitochondrial metabolism to impair malignant growth.

Beuster G, Zarse K, Kaleta C, Thierbach R, Kiehntopf M, Steinberg P, Schuster S, Ristow M. Beuster G, et al. Among authors: thierbach r. J Biol Chem. 2011 Jun 24;286(25):22323-30. doi: 10.1074/jbc.M110.205229. Epub 2011 May 3. J Biol Chem. 2011. PMID: 21540181 Free PMC article.

2

Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited.

Schulz TJ, Thierbach R, Voigt A, Drewes G, Mietzner B, Steinberg P, Pfeiffer AF, Ristow M. Schulz TJ, et al. Among authors: thierbach r. J Biol Chem. 2006 Jan 13;281(2):977-81. doi: 10.1074/jbc.M511064200. Epub 2005 Nov 1. J Biol Chem. 2006. PMID: 16263703 Free article.

3

Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice.

Thierbach R, Schulz TJ, Isken F, Voigt A, Mietzner B, Drewes G, von Kleist-Retzow JC, Wiesner RJ, Magnuson MA, Puccio H, Pfeiffer AF, Steinberg P, Ristow M. Thierbach R, et al. Hum Mol Genet. 2005 Dec 15;14(24):3857-64. doi: 10.1093/hmg/ddi410. Epub 2005 Nov 8. Hum Mol Genet. 2005. PMID: 16278235

4

Activation of mitochondrial energy metabolism protects against cardiac failure.

Schulz TJ, Westermann D, Isken F, Voigt A, Laube B, Thierbach R, Kuhlow D, Zarse K, Schomburg L, Pfeiffer AF, Tschöpe C, Ristow M. Schulz TJ, et al. Among authors: thierbach r. Aging (Albany NY). 2010 Nov;2(11):843-53. doi: 10.18632/aging.100234. Aging (Albany NY). 2010. PMID: 21084725 Free PMC article.

5

Automated soft agar assay for the high-throughput screening of anticancer compounds.

Thierbach R, Steinberg P. Thierbach R, et al. Anal Biochem. 2009 Apr 15;387(2):318-20. doi: 10.1016/j.ab.2009.01.029. Epub 2009 Feb 11. Anal Biochem. 2009. PMID: 19454240

6

Specific alterations of carbohydrate metabolism are associated with hepatocarcinogenesis in mitochondrially impaired mice.

Thierbach R, Florian S, Wolfrum K, Voigt A, Drewes G, Blume U, Bannasch P, Ristow M, Steinberg P. Thierbach R, et al. Hum Mol Genet. 2012 Feb 1;21(3):656-63. doi: 10.1093/hmg/ddr499. Epub 2011 Nov 3. Hum Mol Genet. 2012. PMID: 22052287

7

Reduced expression of mitochondrial frataxin in mice exacerbates diet-induced obesity.

Pomplun D, Voigt A, Schulz TJ, Thierbach R, Pfeiffer AF, Ristow M. Pomplun D, et al. Among authors: thierbach r. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6377-81. doi: 10.1073/pnas.0611631104. Epub 2007 Apr 2. Proc Natl Acad Sci U S A. 2007. PMID: 17404227 Free PMC article.

8

The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals.

Thierbach R, Drewes G, Fusser M, Voigt A, Kuhlow D, Blume U, Schulz TJ, Reiche C, Glatt H, Epe B, Steinberg P, Ristow M. Thierbach R, et al. Biochem J. 2010 Nov 15;432(1):165-72. doi: 10.1042/BJ20101116. Biochem J. 2010. PMID: 20819074 Free PMC article.

9

Variable expression of Cre recombinase transgenes precludes reliable prediction of tissue-specific gene disruption by tail-biopsy genotyping.

Schulz TJ, Glaubitz M, Kuhlow D, Thierbach R, Birringer M, Steinberg P, Pfeiffer AF, Ristow M. Schulz TJ, et al. Among authors: thierbach r. PLoS One. 2007 Oct 10;2(10):e1013. doi: 10.1371/journal.pone.0001013. PLoS One. 2007. PMID: 17925861 Free PMC article.

10

Time-resolved functional analysis of acute impairment of frataxin expression in an inducible cell model of Friedreich ataxia.

Poburski D, Boerner JB, Koenig M, Ristow M, Thierbach R. Poburski D, et al. Among authors: thierbach r. Biol Open. 2016 May 15;5(5):654-61. doi: 10.1242/bio.017004. Biol Open. 2016. PMID: 27106929 Free PMC article.

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