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Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease.
Masliah E, Rockenstein E, Mante M, Crews L, Spencer B, Adame A, Patrick C, Trejo M, Ubhi K, Rohn TT, Mueller-Steiner S, Seubert P, Barbour R, McConlogue L, Buttini M, Games D, Schenk D. Masliah E, et al. Among authors: mcconlogue l. PLoS One. 2011 Apr 29;6(4):e19338. doi: 10.1371/journal.pone.0019338. PLoS One. 2011. Retraction in: PLoS One. 2024 Nov 13;19(11):e0313936. doi: 10.1371/journal.pone.0313936 PMID: 21559417 Free PMC article. Retracted.
Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease.
Gardai SJ, Mao W, Schüle B, Babcock M, Schoebel S, Lorenzana C, Alexander J, Kim S, Glick H, Hilton K, Fitzgerald JK, Buttini M, Chiou SS, McConlogue L, Anderson JP, Schenk DB, Bard F, Langston JW, Yednock T, Johnston JA. Gardai SJ, et al. Among authors: mcconlogue l. PLoS One. 2013 Aug 23;8(8):e71634. doi: 10.1371/journal.pone.0071634. eCollection 2013. PLoS One. 2013. PMID: 24058406 Free PMC article.
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease.
Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, Callaway K, Anderson JP, Jobling MF, Buell AK, Yednock TA, Knowles TP, Vendruscolo M, Christodoulou J, Dobson CM, Schenk D, McConlogue L. Tóth G, et al. Among authors: mcconlogue l. PLoS One. 2014 Feb 14;9(2):e87133. doi: 10.1371/journal.pone.0087133. eCollection 2014. PLoS One. 2014. PMID: 24551051 Free PMC article.
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions.
Tóth G, Neumann T, Berthet A, Masliah E, Spencer B, Tao J, Jobling MF, Gardai SJ, Bertoncini CW, Cremades N, Bova M, Ballaron S, Chen XH, Mao W, Nguyen P, Tabios MC, Tambe MA, Rochet JC, Junker HD, Schwizer D, Sekul R, Ott I, Anderson JP, Szoke B, Hoffman W, Christodoulou J, Yednock T, Agard DA, Schenk D, McConlogue L. Tóth G, et al. Among authors: mcconlogue l. Sci Rep. 2019 Nov 18;9(1):16947. doi: 10.1038/s41598-019-52598-4. Sci Rep. 2019. PMID: 31740740 Free PMC article.
Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease.
Rockenstein EM, McConlogue L, Tan H, Power M, Masliah E, Mucke L. Rockenstein EM, et al. Among authors: mcconlogue l. J Biol Chem. 1995 Nov 24;270(47):28257-67. doi: 10.1074/jbc.270.47.28257. J Biol Chem. 1995. PMID: 7499323 Free article.
Recently, a transgenic model was established in which platelet-derived growth factor (PDGF) promoter-driven neuronal expression of an alternatively spliced hAPP minigene resulted in prominent AD-type neuropathology (Games, D., Adams, D., Alessandrini, R., Barbour, R., Berthelette …
Recently, a transgenic model was established in which platelet-derived growth factor (PDGF) promoter-driven neuronal expression of an altern …
46 results