A synthetic peptide corresponding to a sequence in the GTPase activating protein inhibits p21ras stimulation and promotes guanine nucleotide exchange.
Rubinfeld B, Wong G, Bekesi E, Wood A, Heimer E, McCormick F, Polakis P.
Rubinfeld B, et al. Among authors: mccormick f.
Int J Pept Protein Res. 1991 Jul;38(1):47-53. doi: 10.1111/j.1399-3011.1991.tb01408.x.
Int J Pept Protein Res. 1991.
PMID: 1938104
Amino acid sequence homology between the GTPase Activating Protein (GAP) and the GTP-binding regulatory protein, Gs alpha, suggests that a specific region of GAP primary structure (residues 891-898) may be involved in its stimulation of p21ras GTP hydrolytic activity (McCormic …
Amino acid sequence homology between the GTPase Activating Protein (GAP) and the GTP-binding regulatory protein, Gs alpha, suggests that a s …