He X - Search Results

1

Identification of a novel inhibitor of the canonical Wnt pathway.

Park K, Lee K, Zhang B, Zhou T, He X, Gao G, Murray AR, Ma JX. Park K, et al. Among authors: he x. Mol Cell Biol. 2011 Jul;31(14):3038-51. doi: 10.1128/MCB.01211-10. Epub 2011 May 16. Mol Cell Biol. 2011. PMID: 21576363 Free PMC article.

2

Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression.

Zhang W, Chen X, Kato Y, Evans PM, Yuan S, Yang J, Rychahou PG, Yang VW, He X, Evers BM, Liu C. Zhang W, et al. Among authors: he x. Mol Cell Biol. 2006 Mar;26(6):2055-64. doi: 10.1128/MCB.26.6.2055-2064.2006. Mol Cell Biol. 2006. PMID: 16507986 Free PMC article.

3

Blocking the Wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family.

Zhang B, Abreu JG, Zhou K, Chen Y, Hu Y, Zhou T, He X, Ma JX. Zhang B, et al. Among authors: he x. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6900-5. doi: 10.1073/pnas.0906764107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351274 Free PMC article.

4

Wnt signaling activates MFSD2A to suppress vascular endothelial transcytosis and maintain blood-retinal barrier.

Wang Z, Liu CH, Huang S, Fu Z, Tomita Y, Britton WR, Cho SS, Chen CT, Sun Y, Ma JX, He X, Chen J. Wang Z, et al. Among authors: he x. Sci Adv. 2020 Aug 28;6(35):eaba7457. doi: 10.1126/sciadv.aba7457. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32923627 Free PMC article.

5

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor.

Semënov M, Tamai K, He X. Semënov M, et al. Among authors: he x. J Biol Chem. 2005 Jul 22;280(29):26770-5. doi: 10.1074/jbc.M504308200. Epub 2005 May 20. J Biol Chem. 2005. PMID: 15908424 Free article.

6

The pseudoreceptor BMP and activin membrane-bound inhibitor positively modulates Wnt/beta-catenin signaling.

Lin Z, Gao C, Ning Y, He X, Wu W, Chen YG. Lin Z, et al. Among authors: he x. J Biol Chem. 2008 Nov 28;283(48):33053-8. doi: 10.1074/jbc.M804039200. Epub 2008 Oct 6. J Biol Chem. 2008. PMID: 18838381 Free PMC article.

7

Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling.

Zhong H, Zou H, Semenov MV, Moshinsky D, He X, Huang H, Li S, Quan J, Yang Z, Lin S. Zhong H, et al. Among authors: he x. Mol Biosyst. 2009 Nov;5(11):1356-60. doi: 10.1039/b905752h. Epub 2009 Aug 12. Mol Biosyst. 2009. PMID: 19823752 Free PMC article.

8

Destruction of a destructor: a new avenue for cancer therapeutics targeting the Wnt pathway.

Liu C, He X. Liu C, et al. Among authors: he x. J Mol Cell Biol. 2010 Apr;2(2):70-3. doi: 10.1093/jmcb/mjp040. Epub 2009 Dec 11. J Mol Cell Biol. 2010. PMID: 20008332 Free PMC article.

9

Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling.

Chen S, Bubeck D, MacDonald BT, Liang WX, Mao JH, Malinauskas T, Llorca O, Aricescu AR, Siebold C, He X, Jones EY. Chen S, et al. Among authors: he x. Dev Cell. 2011 Nov 15;21(5):848-61. doi: 10.1016/j.devcel.2011.09.007. Epub 2011 Oct 13. Dev Cell. 2011. PMID: 22000855 Free PMC article.

10

Disabled-2 (Dab2) inhibits Wnt/β-catenin signalling by binding LRP6 and promoting its internalization through clathrin.

Jiang Y, He X, Howe PH. Jiang Y, et al. Among authors: he x. EMBO J. 2012 May 16;31(10):2336-49. doi: 10.1038/emboj.2012.83. Epub 2012 Apr 10. EMBO J. 2012. PMID: 22491013 Free PMC article.

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