Komatsu N - Search Results

1

Clinical significance of aberrant DNA methylation in childhood acute lymphoblastic leukemia.

Takeuchi S, Matsushita M, Zimmermann M, Ikezoe T, Komatsu N, Seriu T, Schrappe M, Bartram CR, Koeffler HP. Takeuchi S, et al. Among authors: komatsu n. Leuk Res. 2011 Oct;35(10):1345-9. doi: 10.1016/j.leukres.2011.04.015. Epub 2011 May 17. Leuk Res. 2011. PMID: 21592569 Free PMC article.

2

Blockade of MEK/ERK signaling enhances sunitinib-induced growth inhibition and apoptosis of leukemia cells possessing activating mutations of the FLT3 gene.

Nishioka C, Ikezoe T, Yang J, Takeshita A, Taniguchi A, Komatsu N, Togitani K, Koeffler HP, Yokoyama A. Nishioka C, et al. Among authors: komatsu n. Leuk Res. 2008 Jun;32(6):865-72. doi: 10.1016/j.leukres.2007.09.017. Epub 2007 Nov 5. Leuk Res. 2008. PMID: 17983653

3

The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling.

Ikezoe T, Nishioka C, Tasaka T, Yang Y, Komatsu N, Togitani K, Koeffler HP, Taguchi H. Ikezoe T, et al. Among authors: komatsu n. Mol Cancer Ther. 2006 Oct;5(10):2522-30. doi: 10.1158/1535-7163.MCT-06-0071. Mol Cancer Ther. 2006. PMID: 17041096

4

A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia.

Ikezoe T, Yang J, Nishioka C, Tasaka T, Taniguchi A, Kuwayama Y, Komatsu N, Bandobashi K, Togitani K, Koeffler HP, Taguchi H. Ikezoe T, et al. Among authors: komatsu n. Mol Cancer Ther. 2007 Jun;6(6):1851-7. doi: 10.1158/1535-7163.MCT-07-0067. Epub 2007 May 31. Mol Cancer Ther. 2007. PMID: 17541033

5

Histone deacetylase inhibitors induce growth arrest and apoptosis of HTLV-1-infected T-cells via blockade of signaling by nuclear factor kappaB.

Nishioka C, Ikezoe T, Yang J, Komatsu N, Bandobashi K, Taniguchi A, Kuwayama Y, Togitani K, Koeffler HP, Taguchi H. Nishioka C, et al. Among authors: komatsu n. Leuk Res. 2008 Feb;32(2):287-96. doi: 10.1016/j.leukres.2007.05.026. Epub 2007 Jul 20. Leuk Res. 2008. PMID: 17644177

6

Blockade of MEK signaling potentiates 5-Aza-2'-deoxycytidine-induced apoptosis and upregulation of p21(waf1) in acute myelogenous leukemia cells.

Nishioka C, Ikezoe T, Yang J, Komatsu N, Koeffler HP, Yokoyama A. Nishioka C, et al. Among authors: komatsu n. Int J Cancer. 2009 Sep 1;125(5):1168-76. doi: 10.1002/ijc.24377. Int J Cancer. 2009. PMID: 19422044

7

Mutations of the E2F4 gene in hematological malignancies having microsatellite instability.

Komatsu N, Takeuchi S, Ikezoe T, Tasaka T, Hatta Y, Machida H, Williamson IK, Bartram CR, Koeffler HP, Taguchi H. Komatsu N, et al. Blood. 2000 Feb 15;95(4):1509-10. Blood. 2000. PMID: 10666234 Free article.

8

SAHA, a HDAC inhibitor, has profound anti-growth activity against non-small cell lung cancer cells.

Komatsu N, Kawamata N, Takeuchi S, Yin D, Chien W, Miller CW, Koeffler HP. Komatsu N, et al. Oncol Rep. 2006 Jan;15(1):187-91. Oncol Rep. 2006. PMID: 16328054

9

AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo.

Yang J, Ikezoe T, Nishioka C, Tasaka T, Taniguchi A, Kuwayama Y, Komatsu N, Bandobashi K, Togitani K, Koeffler HP, Taguchi H, Yokoyama A. Yang J, et al. Among authors: komatsu n. Blood. 2007 Sep 15;110(6):2034-40. doi: 10.1182/blood-2007-02-073700. Epub 2007 May 10. Blood. 2007. PMID: 17495131 Free article.

10

ZD6474 induces growth arrest and apoptosis of human leukemia cells, which is enhanced by concomitant use of a novel MEK inhibitor, AZD6244.

Nishioka C, Ikezoe T, Takeshita A, Yang J, Tasaka T, Yang Y, Kuwayama Y, Komatsu N, Togitani K, Koeffler HP, Taguchi H. Nishioka C, et al. Among authors: komatsu n. Leukemia. 2007 Jun;21(6):1308-10. doi: 10.1038/sj.leu.2404647. Epub 2007 Mar 15. Leukemia. 2007. PMID: 17361222 No abstract available.

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