Smith PJ - Search Results

1

Absorption of the novel artemisinin derivatives artemisone and artemiside: potential application of Pheroid™ technology.

Steyn JD, Wiesner L, du Plessis LH, Grobler AF, Smith PJ, Chan WC, Haynes RK, Kotzé AF. Steyn JD, et al. Among authors: smith pj. Int J Pharm. 2011 Jul 29;414(1-2):260-6. doi: 10.1016/j.ijpharm.2011.05.003. Epub 2011 May 7. Int J Pharm. 2011. PMID: 21596127

2

Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte Stages.

Coertzen D, Reader J, van der Watt M, Nondaba SH, Gibhard L, Wiesner L, Smith P, D'Alessandro S, Taramelli D, Wong HN, du Preez JL, Wu RWK, Birkholtz LM, Haynes RK. Coertzen D, et al. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e02214-17. doi: 10.1128/AAC.02214-17. Print 2018 Aug. Antimicrob Agents Chemother. 2018. PMID: 29866868 Free PMC article.

3

A liquid-liquid LC/MS/MS assay for the determination of artemether and DHA in malaria patient samples.

Wiesner L, Govender K, Meredith SA, Norman J, Smith PJ. Wiesner L, et al. Among authors: smith pj. J Pharm Biomed Anal. 2011 May 15;55(2):373-8. doi: 10.1016/j.jpba.2011.01.036. Epub 2011 Feb 4. J Pharm Biomed Anal. 2011. PMID: 21353430

4

Synthesis and in vitro biological evaluation of aminoacridines and artemisinin-acridine hybrids.

Joubert JP, Smit FJ, du Plessis L, Smith PJ, N'Da DD. Joubert JP, et al. Among authors: smith pj. Eur J Pharm Sci. 2014 Jun 2;56:16-27. doi: 10.1016/j.ejps.2014.01.014. Epub 2014 Feb 18. Eur J Pharm Sci. 2014. PMID: 24560941

5

In Vitro and In Vivo Pharmacokinetics of Aminoalkylated Diarylpropanes NP085 and NP102.

Gibhard L, Pravin K, Abay E, Wilhelm A, Swart K, Lawrence N, Khoury R, van der Westhuizen J, Smith P, Wiesner L. Gibhard L, et al. Antimicrob Agents Chemother. 2016 Apr 22;60(5):3065-9. doi: 10.1128/AAC.02104-15. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26953201 Free PMC article.

6

Optimal 10-Aminoartemisinins With Potent Transmission-Blocking Capabilities for New Artemisinin Combination Therapies-Activities Against Blood Stage P. falciparum Including PfKI3 C580Y Mutants and Liver Stage P. berghei Parasites.

Wong HN, Padín-Irizarry V, van der Watt ME, Reader J, Liebenberg W, Wiesner L, Smith P, Eribez K, Winzeler EA, Kyle DE, Birkholtz LM, Coertzen D, Haynes RK. Wong HN, et al. Front Chem. 2020 Jan 10;7:901. doi: 10.3389/fchem.2019.00901. eCollection 2019. Front Chem. 2020. PMID: 31998692 Free PMC article.

7

A Pharmacokinetic Study of Antimalarial 3,5-Diaryl-2-aminopyridine Derivatives.

Dambuza N, Smith P, Evans A, Taylor D, Chibale K, Wiesner L. Dambuza N, et al. Malar Res Treat. 2015;2015:405962. doi: 10.1155/2015/405962. Epub 2015 Mar 29. Malar Res Treat. 2015. PMID: 25893131 Free PMC article.

8

Antiplasmodial activity, in vivo pharmacokinetics and anti-malarial efficacy evaluation of hydroxypyridinone hybrids in a mouse model.

Dambuza NS, Smith P, Evans A, Norman J, Taylor D, Andayi A, Egan T, Chibale K, Wiesner L. Dambuza NS, et al. Malar J. 2015 Dec 16;14:505. doi: 10.1186/s12936-015-1032-5. Malar J. 2015. PMID: 26671222 Free PMC article.

9

An LC-MS/MS method for the determination of ofloxacin in 20 μl human plasma.

Meredith SA, Smith PJ, Norman J, Wiesner L. Meredith SA, et al. Among authors: smith pj. J Pharm Biomed Anal. 2012 Jan 25;58:177-81. doi: 10.1016/j.jpba.2011.09.030. Epub 2011 Oct 1. J Pharm Biomed Anal. 2012. PMID: 22018893

10

Oral lipid-based nanoformulation of tafenoquine enhanced bioavailability and blood stage antimalarial efficacy and led to a reduction in human red blood cell loss in mice.

Melariri P, Kalombo L, Nkuna P, Dube A, Hayeshi R, Ogutu B, Gibhard L, deKock C, Smith P, Wiesner L, Swai H. Melariri P, et al. Int J Nanomedicine. 2015 Feb 20;10:1493-503. doi: 10.2147/IJN.S76317. eCollection 2015. Int J Nanomedicine. 2015. PMID: 25759576 Free PMC article.

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