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140 results

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Page 1
Large-scale asymmetric synthesis of a cathepsin S inhibitor.
Lorenz JC, Busacca CA, Feng X, Grinberg N, Haddad N, Johnson J, Kapadia S, Lee H, Saha A, Sarvestani M, Spinelli EM, Varsolona R, Wei X, Zeng X, Senanayake CH. Lorenz JC, et al. Among authors: grinberg n. J Org Chem. 2010 Feb 19;75(4):1155-61. doi: 10.1021/jo9022809. J Org Chem. 2010. PMID: 20102230
Efficient asymmetric synthesis of P-chiral phosphine oxides via properly designed and activated benzoxazaphosphinine-2-oxide agents.
Han ZS, Goyal N, Herbage MA, Sieber JD, Qu B, Xu Y, Li Z, Reeves JT, Desrosiers JN, Ma S, Grinberg N, Lee H, Mangunuru HP, Zhang Y, Krishnamurthy D, Lu BZ, Song JJ, Wang G, Senanayake CH. Han ZS, et al. Among authors: grinberg n. J Am Chem Soc. 2013 Feb 20;135(7):2474-7. doi: 10.1021/ja312352p. Epub 2013 Feb 6. J Am Chem Soc. 2013. PMID: 23369026
Development of a large scale asymmetric synthesis of the glucocorticoid agonist BI 653048 BS H3PO4.
Reeves JT, Fandrick DR, Tan Z, Song JJ, Rodriguez S, Qu B, Kim S, Niemeier O, Li Z, Byrne D, Campbell S, Chitroda A, DeCroos P, Fachinger T, Fuchs V, Gonnella NC, Grinberg N, Haddad N, Jäger B, Lee H, Lorenz JC, Ma S, Narayanan BA, Nummy LJ, Premasiri A, Roschangar F, Sarvestani M, Shen S, Spinelli E, Sun X, Varsolona RJ, Yee N, Brenner M, Senanayake CH. Reeves JT, et al. Among authors: grinberg n. J Org Chem. 2013 Apr 19;78(8):3616-35. doi: 10.1021/jo400079z. Epub 2013 Apr 1. J Org Chem. 2013. PMID: 23544738
Zinc catalyzed and mediated asymmetric propargylation of trifluoromethyl ketones with a propargyl boronate.
Fandrick DR, Reeves JT, Bakonyi JM, Nyalapatla PR, Tan Z, Niemeier O, Akalay D, Fandrick KR, Wohlleben W, Ollenberger S, Song JJ, Sun X, Qu B, Haddad N, Sanyal S, Shen S, Ma S, Byrne D, Chitroda A, Fuchs V, Narayanan BA, Grinberg N, Lee H, Yee N, Brenner M, Senanayake CH. Fandrick DR, et al. Among authors: grinberg n. J Org Chem. 2013 Apr 19;78(8):3592-615. doi: 10.1021/jo400080y. Epub 2013 Apr 1. J Org Chem. 2013. PMID: 23544787
Design and synthesis of chiral oxathiozinone scaffolds: efficient synthesis of hindered enantiopure sulfinamides and sulfinyl ketimines.
Han ZS, Herbage MA, Mangunuru HP, Xu Y, Zhang L, Reeves JT, Sieber JD, Li Z, DeCroos P, Zhang Y, Li G, Li N, Ma S, Grinberg N, Wang X, Goyal N, Krishnamurthy D, Lu B, Song JJ, Wang G, Senanayake CH. Han ZS, et al. Among authors: grinberg n. Angew Chem Int Ed Engl. 2013 Jun 24;52(26):6713-7. doi: 10.1002/anie.201301676. Epub 2013 May 15. Angew Chem Int Ed Engl. 2013. PMID: 23677810 No abstract available.
Facile entry to an efficient and practical enantioselective synthesis of a polycyclic cholesteryl ester transfer protein inhibitor.
Han ZS, Xu Y, Fandrick DR, Rodriguez S, Li Z, Qu B, Gonnella NC, Sanyal S, Reeves JT, Ma S, Grinberg N, Haddad N, Krishnamurthy D, Song JJ, Yee NK, Pfrengle W, Ostermeier M, Schnaubelt J, Leuter Z, Steigmiller S, Däubler J, Stehle E, Neumann L, Trieselmann T, Tielmann P, Buba A, Hamm R, Koch G, Renner S, Dehli JR, Schmelcher F, Stange C, Mack J, Soyka R, Senanayake CH. Han ZS, et al. Among authors: grinberg n. Org Lett. 2014 Aug 15;16(16):4142-5. doi: 10.1021/ol501833g. Epub 2014 Aug 1. Org Lett. 2014. PMID: 25084526
140 results