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Efficient asymmetric synthesis of P-chiral phosphine oxides via properly designed and activated benzoxazaphosphinine-2-oxide agents.
Han ZS, Goyal N, Herbage MA, Sieber JD, Qu B, Xu Y, Li Z, Reeves JT, Desrosiers JN, Ma S, Grinberg N, Lee H, Mangunuru HP, Zhang Y, Krishnamurthy D, Lu BZ, Song JJ, Wang G, Senanayake CH. Han ZS, et al. Among authors: xu y. J Am Chem Soc. 2013 Feb 20;135(7):2474-7. doi: 10.1021/ja312352p. Epub 2013 Feb 6. J Am Chem Soc. 2013. PMID: 23369026
Design and synthesis of chiral oxathiozinone scaffolds: efficient synthesis of hindered enantiopure sulfinamides and sulfinyl ketimines.
Han ZS, Herbage MA, Mangunuru HP, Xu Y, Zhang L, Reeves JT, Sieber JD, Li Z, DeCroos P, Zhang Y, Li G, Li N, Ma S, Grinberg N, Wang X, Goyal N, Krishnamurthy D, Lu B, Song JJ, Wang G, Senanayake CH. Han ZS, et al. Among authors: xu y. Angew Chem Int Ed Engl. 2013 Jun 24;52(26):6713-7. doi: 10.1002/anie.201301676. Epub 2013 May 15. Angew Chem Int Ed Engl. 2013. PMID: 23677810 No abstract available.
Facile entry to an efficient and practical enantioselective synthesis of a polycyclic cholesteryl ester transfer protein inhibitor.
Han ZS, Xu Y, Fandrick DR, Rodriguez S, Li Z, Qu B, Gonnella NC, Sanyal S, Reeves JT, Ma S, Grinberg N, Haddad N, Krishnamurthy D, Song JJ, Yee NK, Pfrengle W, Ostermeier M, Schnaubelt J, Leuter Z, Steigmiller S, Däubler J, Stehle E, Neumann L, Trieselmann T, Tielmann P, Buba A, Hamm R, Koch G, Renner S, Dehli JR, Schmelcher F, Stange C, Mack J, Soyka R, Senanayake CH. Han ZS, et al. Among authors: xu y. Org Lett. 2014 Aug 15;16(16):4142-5. doi: 10.1021/ol501833g. Epub 2014 Aug 1. Org Lett. 2014. PMID: 25084526
Development of a Scalable, Chromatography-Free Synthesis of t-Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF3-Alcohol Derivative with High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation.
Sieber JD, Rodriguez S, Frutos R, Buono F, Zhang Y, Li N, Qu B, Premasiri A, Li Z, Han ZS, Xu Y, Byrne D, Haddad N, Lorenz J, Grinberg N, Kurouski D, Lee H, Narayanan B, Nummy L, Mulder J, Brown JD, Granger A, Gao J, Krawiec M, Williams Z, Pennino S, Song JJ, Hossain A, Yee NK, Busacca C, Roschangar F, Xin Y, Mao Z, Zhang X, Hong Y, Senanayake CH. Sieber JD, et al. Among authors: xu y. J Org Chem. 2018 Feb 2;83(3):1448-1461. doi: 10.1021/acs.joc.7b03022. Epub 2018 Jan 23. J Org Chem. 2018. PMID: 29323903
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