Hamm HE - Search Results

1

Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit.

Van Eps N, Preininger AM, Alexander N, Kaya AI, Meier S, Meiler J, Hamm HE, Hubbell WL. Van Eps N, et al. Among authors: hamm he. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9420-4. doi: 10.1073/pnas.1105810108. Epub 2011 May 23. Proc Natl Acad Sci U S A. 2011. PMID: 21606326 Free PMC article.

2

Structural and dynamical changes in an alpha-subunit of a heterotrimeric G protein along the activation pathway.

Van Eps N, Oldham WM, Hamm HE, Hubbell WL. Van Eps N, et al. Among authors: hamm he. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16194-9. doi: 10.1073/pnas.0607972103. Epub 2006 Oct 19. Proc Natl Acad Sci U S A. 2006. PMID: 17053066 Free PMC article.

3

Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins.

Oldham WM, Van Eps N, Preininger AM, Hubbell WL, Hamm HE. Oldham WM, et al. Among authors: hamm he. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7927-32. doi: 10.1073/pnas.0702623104. Epub 2007 Apr 26. Proc Natl Acad Sci U S A. 2007. PMID: 17463080 Free PMC article.

4

G protein signaling: insights from new structures.

Preininger AM, Hamm HE. Preininger AM, et al. Among authors: hamm he. Sci STKE. 2004 Jan 27;2004(218):re3. doi: 10.1126/stke.2182004re3. Sci STKE. 2004. PMID: 14762218 Review.

5

Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins.

Oldham WM, Van Eps N, Preininger AM, Hubbell WL, Hamm HE. Oldham WM, et al. Among authors: hamm he. Nat Struct Mol Biol. 2006 Sep;13(9):772-7. doi: 10.1038/nsmb1129. Epub 2006 Aug 6. Nat Struct Mol Biol. 2006. PMID: 16892066

6

Allosteric mechanisms of G protein-Coupled Receptor signaling: a structural perspective.

Thaker TM, Kaya AI, Preininger AM, Hamm HE, Iverson TM. Thaker TM, et al. Among authors: hamm he. Methods Mol Biol. 2012;796:133-74. doi: 10.1007/978-1-61779-334-9_8. Methods Mol Biol. 2012. PMID: 22052489 Free PMC article.

7

Linking receptor activation to changes in Sw I and II of Gα proteins.

Hamm HE, Kaya AI, Gilbert JA 3rd, Preininger AM. Hamm HE, et al. J Struct Biol. 2013 Oct;184(1):63-74. doi: 10.1016/j.jsb.2013.02.016. Epub 2013 Mar 4. J Struct Biol. 2013. PMID: 23466875 Free PMC article.

8

Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release.

Alexander NS, Preininger AM, Kaya AI, Stein RA, Hamm HE, Meiler J. Alexander NS, et al. Among authors: hamm he. Nat Struct Mol Biol. 2014 Jan;21(1):56-63. doi: 10.1038/nsmb.2705. Epub 2013 Dec 1. Nat Struct Mol Biol. 2014. PMID: 24292645 Free PMC article.

9

A transient interaction between the phosphate binding loop and switch I contributes to the allosteric network between receptor and nucleotide in Gαi1.

Thaker TM, Sarwar M, Preininger AM, Hamm HE, Iverson TM. Thaker TM, et al. Among authors: hamm he. J Biol Chem. 2014 Apr 18;289(16):11331-11341. doi: 10.1074/jbc.M113.539064. Epub 2014 Mar 4. J Biol Chem. 2014. PMID: 24596087 Free PMC article.

10

A conserved phenylalanine as a relay between the α5 helix and the GDP binding region of heterotrimeric Gi protein α subunit.

Kaya AI, Lokits AD, Gilbert JA, Iverson TM, Meiler J, Hamm HE. Kaya AI, et al. Among authors: hamm he. J Biol Chem. 2014 Aug 29;289(35):24475-87. doi: 10.1074/jbc.M114.572875. Epub 2014 Jul 18. J Biol Chem. 2014. PMID: 25037222 Free PMC article.

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