Preininger AM - Search Results

1

Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit.

Van Eps N, Preininger AM, Alexander N, Kaya AI, Meier S, Meiler J, Hamm HE, Hubbell WL. Van Eps N, et al. Among authors: preininger am. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9420-4. doi: 10.1073/pnas.1105810108. Epub 2011 May 23. Proc Natl Acad Sci U S A. 2011. PMID: 21606326 Free PMC article.

2

Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins.

Oldham WM, Van Eps N, Preininger AM, Hubbell WL, Hamm HE. Oldham WM, et al. Among authors: preininger am. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7927-32. doi: 10.1073/pnas.0702623104. Epub 2007 Apr 26. Proc Natl Acad Sci U S A. 2007. PMID: 17463080 Free PMC article.

3

Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation.

Medkova M, Preininger AM, Yu NJ, Hubbell WL, Hamm HE. Medkova M, et al. Among authors: preininger am. Biochemistry. 2002 Aug 6;41(31):9962-72. doi: 10.1021/bi0255726. Biochemistry. 2002. PMID: 12146960

4

The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution.

Preininger AM, Van Eps N, Yu NJ, Medkova M, Hubbell WL, Hamm HE. Preininger AM, et al. Biochemistry. 2003 Jul 8;42(26):7931-41. doi: 10.1021/bi0345438. Biochemistry. 2003. PMID: 12834345

5

G protein signaling: insights from new structures.

Preininger AM, Hamm HE. Preininger AM, et al. Sci STKE. 2004 Jan 27;2004(218):re3. doi: 10.1126/stke.2182004re3. Sci STKE. 2004. PMID: 14762218 Review.

6

Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins.

Oldham WM, Van Eps N, Preininger AM, Hubbell WL, Hamm HE. Oldham WM, et al. Among authors: preininger am. Nat Struct Mol Biol. 2006 Sep;13(9):772-7. doi: 10.1038/nsmb1129. Epub 2006 Aug 6. Nat Struct Mol Biol. 2006. PMID: 16892066

7

Allosteric mechanisms of G protein-Coupled Receptor signaling: a structural perspective.

Thaker TM, Kaya AI, Preininger AM, Hamm HE, Iverson TM. Thaker TM, et al. Among authors: preininger am. Methods Mol Biol. 2012;796:133-74. doi: 10.1007/978-1-61779-334-9_8. Methods Mol Biol. 2012. PMID: 22052489 Free PMC article.

8

Linking receptor activation to changes in Sw I and II of Gα proteins.

Hamm HE, Kaya AI, Gilbert JA 3rd, Preininger AM. Hamm HE, et al. Among authors: preininger am. J Struct Biol. 2013 Oct;184(1):63-74. doi: 10.1016/j.jsb.2013.02.016. Epub 2013 Mar 4. J Struct Biol. 2013. PMID: 23466875 Free PMC article.

9

Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release.

Alexander NS, Preininger AM, Kaya AI, Stein RA, Hamm HE, Meiler J. Alexander NS, et al. Among authors: preininger am. Nat Struct Mol Biol. 2014 Jan;21(1):56-63. doi: 10.1038/nsmb.2705. Epub 2013 Dec 1. Nat Struct Mol Biol. 2014. PMID: 24292645 Free PMC article.

10

A transient interaction between the phosphate binding loop and switch I contributes to the allosteric network between receptor and nucleotide in Gαi1.

Thaker TM, Sarwar M, Preininger AM, Hamm HE, Iverson TM. Thaker TM, et al. Among authors: preininger am. J Biol Chem. 2014 Apr 18;289(16):11331-11341. doi: 10.1074/jbc.M113.539064. Epub 2014 Mar 4. J Biol Chem. 2014. PMID: 24596087 Free PMC article.

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