Birnbaum MJ - Search Results

1

Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling.

Miller RA, Chu Q, Le Lay J, Scherer PE, Ahima RS, Kaestner KH, Foretz M, Viollet B, Birnbaum MJ. Miller RA, et al. Among authors: birnbaum mj. J Clin Invest. 2011 Jun;121(6):2518-28. doi: 10.1172/JCI45942. Epub 2011 May 23. J Clin Invest. 2011. PMID: 21606593 Free PMC article.

2

Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP.

Miller RA, Chu Q, Xie J, Foretz M, Viollet B, Birnbaum MJ. Miller RA, et al. Among authors: birnbaum mj. Nature. 2013 Feb 14;494(7436):256-60. doi: 10.1038/nature11808. Epub 2013 Jan 6. Nature. 2013. PMID: 23292513 Free PMC article.

3

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.

Patel K, Foretz M, Marion A, Campbell DG, Gourlay R, Boudaba N, Tournier E, Titchenell P, Peggie M, Deak M, Wan M, Kaestner KH, Göransson O, Viollet B, Gray NS, Birnbaum MJ, Sutherland C, Sakamoto K. Patel K, et al. Among authors: birnbaum mj. Nat Commun. 2014 Aug 4;5:4535. doi: 10.1038/ncomms5535. Nat Commun. 2014. PMID: 25088745 Free PMC article.

4

An energetic tale of AMPK-independent effects of metformin.

Miller RA, Birnbaum MJ. Miller RA, et al. Among authors: birnbaum mj. J Clin Invest. 2010 Jul;120(7):2267-70. doi: 10.1172/JCI43661. Epub 2010 Jun 23. J Clin Invest. 2010. PMID: 20577046 Free PMC article. Review.

5

Role of insulin-like growth factor-binding protein 5 (IGFBP5) in organismal and pancreatic beta-cell growth.

Gleason CE, Ning Y, Cominski TP, Gupta R, Kaestner KH, Pintar JE, Birnbaum MJ. Gleason CE, et al. Among authors: birnbaum mj. Mol Endocrinol. 2010 Jan;24(1):178-92. doi: 10.1210/me.2009-0167. Epub 2009 Nov 6. Mol Endocrinol. 2010. PMID: 19897600 Free PMC article.

6

Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c.

Wan M, Leavens KF, Saleh D, Easton RM, Guertin DA, Peterson TR, Kaestner KH, Sabatini DM, Birnbaum MJ. Wan M, et al. Among authors: birnbaum mj. Cell Metab. 2011 Oct 5;14(4):516-27. doi: 10.1016/j.cmet.2011.09.001. Cell Metab. 2011. PMID: 21982711 Free PMC article.

7

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1.

Lu M, Wan M, Leavens KF, Chu Q, Monks BR, Fernandez S, Ahima RS, Ueki K, Kahn CR, Birnbaum MJ. Lu M, et al. Among authors: birnbaum mj. Nat Med. 2012 Feb 19;18(3):388-95. doi: 10.1038/nm.2686. Nat Med. 2012. PMID: 22344295 Free PMC article.

8

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration.

Sun Z, Miller RA, Patel RT, Chen J, Dhir R, Wang H, Zhang D, Graham MJ, Unterman TG, Shulman GI, Sztalryd C, Bennett MJ, Ahima RS, Birnbaum MJ, Lazar MA. Sun Z, et al. Among authors: birnbaum mj. Nat Med. 2012 Jun;18(6):934-42. doi: 10.1038/nm.2744. Nat Med. 2012. PMID: 22561686 Free PMC article.

9

Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo.

Titchenell PM, Chu Q, Monks BR, Birnbaum MJ. Titchenell PM, et al. Among authors: birnbaum mj. Nat Commun. 2015 May 12;6:7078. doi: 10.1038/ncomms8078. Nat Commun. 2015. PMID: 25963408 Free PMC article.

10

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta).

Cho H, Mu J, Kim JK, Thorvaldsen JL, Chu Q, Crenshaw EB 3rd, Kaestner KH, Bartolomei MS, Shulman GI, Birnbaum MJ. Cho H, et al. Among authors: birnbaum mj. Science. 2001 Jun 1;292(5522):1728-31. doi: 10.1126/science.292.5522.1728. Science. 2001. PMID: 11387480

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