Spokes K - Search Results

1

RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG.

Yuan L, Sacharidou A, Stratman AN, Le Bras A, Zwiers PJ, Spokes K, Bhasin M, Shih SC, Nagy JA, Molema G, Aird WC, Davis GE, Oettgen P. Yuan L, et al. Among authors: spokes k. Blood. 2011 Jul 28;118(4):1145-53. doi: 10.1182/blood-2010-10-315275. Epub 2011 May 31. Blood. 2011. PMID: 21628409 Free PMC article.

2

Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis.

Vijayaraj P, Le Bras A, Mitchell N, Kondo M, Juliao S, Wasserman M, Beeler D, Spokes K, Aird WC, Baldwin HS, Oettgen P. Vijayaraj P, et al. Among authors: spokes k. Development. 2012 Nov;139(21):3973-85. doi: 10.1242/dev.081596. Epub 2012 Aug 29. Development. 2012. PMID: 22932696 Free PMC article.

3

Differential roles for ETS, CREB, and EGR binding sites in mediating VEGF receptor 1 expression in vivo.

Jin E, Liu J, Suehiro J, Yuan L, Okada Y, Nikolova-Krstevski V, Yano K, Janes L, Beeler D, Spokes KC, Li D, Regan E, Shih SC, Oettgen P, Minami T, Aird WC. Jin E, et al. Among authors: spokes kc. Blood. 2009 Dec 24;114(27):5557-66. doi: 10.1182/blood-2009-05-220434. Epub 2009 Oct 12. Blood. 2009. PMID: 19822898 Free PMC article.

4

Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle.

Liu J, Yuan L, Molema G, Regan E, Janes L, Beeler D, Spokes KC, Okada Y, Minami T, Oettgen P, Aird WC. Liu J, et al. Blood. 2011 Jan 6;117(1):342-51. doi: 10.1182/blood-2010-06-287987. Epub 2010 Oct 27. Blood. 2011. PMID: 20980682 Free PMC article.

5

Role of RNA splicing in mediating lineage-specific expression of the von Willebrand factor gene in the endothelium.

Yuan L, Janes L, Beeler D, Spokes KC, Smith J, Li D, Jaminet SC, Oettgen P, Aird WC. Yuan L, et al. Among authors: spokes kc. Blood. 2013 May 23;121(21):4404-12. doi: 10.1182/blood-2012-12-473785. Epub 2013 Mar 25. Blood. 2013. PMID: 23529929 Free PMC article.

6

A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium.

Okada Y, Yano K, Jin E, Funahashi N, Kitayama M, Doi T, Spokes K, Beeler DL, Shih SC, Okada H, Danilov TA, Maynard E, Minami T, Oettgen P, Aird WC. Okada Y, et al. Among authors: spokes k. Circ Res. 2007 Jun 22;100(12):1712-22. doi: 10.1161/01.RES.0000269779.10644.dc. Epub 2007 May 10. Circ Res. 2007. PMID: 17495228

7

A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo.

Okada Y, Jin E, Nikolova-Krstevski V, Yano K, Liu J, Beeler D, Spokes K, Kitayama M, Funahashi N, Doi T, Janes L, Minami T, Oettgen P, Aird WC. Okada Y, et al. Among authors: spokes k. Blood. 2008 Sep 15;112(6):2336-9. doi: 10.1182/blood-2008-01-135079. Epub 2008 Jun 2. Blood. 2008. PMID: 18519813 Free PMC article.

8

Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation.

Zhang G, Yang L, Kim GS, Ryan K, Lu S, O'Donnell RK, Spokes K, Shapiro N, Aird WC, Kluk MJ, Yano K, Sanchez T. Zhang G, et al. Among authors: spokes k. Blood. 2013 Jul 18;122(3):443-55. doi: 10.1182/blood-2012-11-467191. Epub 2013 May 30. Blood. 2013. PMID: 23723450 Free PMC article.

9

A novel class of vascular endothelial growth factor-responsive genes that require forkhead activity for expression.

Abid MR, Shih SC, Otu HH, Spokes KC, Okada Y, Curiel DT, Minami T, Aird WC. Abid MR, et al. J Biol Chem. 2006 Nov 17;281(46):35544-53. doi: 10.1074/jbc.M608620200. Epub 2006 Sep 15. J Biol Chem. 2006. PMID: 16980307 Free article.

10

NADPH oxidase activity selectively modulates vascular endothelial growth factor signaling pathways.

Abid MR, Spokes KC, Shih SC, Aird WC. Abid MR, et al. J Biol Chem. 2007 Nov 30;282(48):35373-85. doi: 10.1074/jbc.M702175200. Epub 2007 Oct 1. J Biol Chem. 2007. PMID: 17908694 Free article.

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