Chen S - Search Results

1

The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis.

Muniz VP, Barnes JM, Paliwal S, Zhang X, Tang X, Chen S, Zamba KD, Cullen JJ, Meyerholz DK, Meyers S, Davis JN, Grossman SR, Henry MD, Quelle DE. Muniz VP, et al. Among authors: chen s. Mol Cancer Res. 2011 Jul;9(7):867-77. doi: 10.1158/1541-7786.MCR-10-0475. Epub 2011 Jun 2. Mol Cancer Res. 2011. PMID: 21636682 Free PMC article.

2

A critical role of Gbetagamma in tumorigenesis and metastasis of breast cancer.

Tang X, Sun Z, Runne C, Madsen J, Domann F, Henry M, Lin F, Chen S. Tang X, et al. Among authors: chen s. J Biol Chem. 2011 Apr 15;286(15):13244-54. doi: 10.1074/jbc.M110.206615. Epub 2011 Feb 24. J Biol Chem. 2011. PMID: 21349837 Free PMC article.

3

The WD40 repeat protein WDR26 binds Gβγ and promotes Gβγ-dependent signal transduction and leukocyte migration.

Sun Z, Tang X, Lin F, Chen S. Sun Z, et al. Among authors: chen s. J Biol Chem. 2011 Dec 23;286(51):43902-43912. doi: 10.1074/jbc.M111.301382. Epub 2011 Nov 7. J Biol Chem. 2011. PMID: 22065575 Free PMC article.

4

The Gβ3 splice variant associated with the C825T gene polymorphism is an unstable and functionally inactive protein.

Sun Z, Runne C, Tang X, Lin F, Chen S. Sun Z, et al. Among authors: chen s. Cell Signal. 2012 Dec;24(12):2349-59. doi: 10.1016/j.cellsig.2012.08.011. Epub 2012 Aug 30. Cell Signal. 2012. PMID: 22940628 Free PMC article.

5

Upregulated WDR26 serves as a scaffold to coordinate PI3K/ AKT pathway-driven breast cancer cell growth, migration, and invasion.

Ye Y, Tang X, Sun Z, Chen S. Ye Y, et al. Among authors: chen s. Oncotarget. 2016 Apr 5;7(14):17854-69. doi: 10.18632/oncotarget.7439. Oncotarget. 2016. PMID: 26895380 Free PMC article.

6

Inhibiting G protein βγ signaling blocks prostate cancer progression and enhances the efficacy of paclitaxel.

Paudyal P, Xie Q, Vaddi PK, Henry MD, Chen S. Paudyal P, et al. Among authors: chen s. Oncotarget. 2017 May 30;8(22):36067-36081. doi: 10.18632/oncotarget.16428. Oncotarget. 2017. PMID: 28415604 Free PMC article.

7

Targeting Gi/o protein-coupled receptor signaling blocks HER2-induced breast cancer development and enhances HER2-targeted therapy.

Lyu C, Ye Y, Lensing MM, Wagner KU, Weigel RJ, Chen S. Lyu C, et al. Among authors: chen s. JCI Insight. 2021 Sep 22;6(18):e150532. doi: 10.1172/jci.insight.150532. JCI Insight. 2021. PMID: 34343132 Free PMC article.

8

Active Gα_i/o Mutants Accelerate Breast Tumor Metastasis via the c-Src Pathway.

Lyu C, Bhimani AK, Draus WT, Weigel R, Chen S. Lyu C, et al. Among authors: chen s. Mol Cell Biol. 2023;43(12):650-663. doi: 10.1080/10985549.2023.2285833. Epub 2023 Dec 20. Mol Cell Biol. 2023. PMID: 38099640

9

Identification and expression patterns of members of the protease-activated receptor (PAR) gene family during zebrafish development.

Xu H, Echemendia N, Chen S, Lin F. Xu H, et al. Among authors: chen s. Dev Dyn. 2011 Jan;240(1):278-87. doi: 10.1002/dvdy.22517. Dev Dyn. 2011. PMID: 21181945 Free PMC article.

10

Gβγ signaling controls the polarization of zebrafish primordial germ cells by regulating Rac activity.

Xu H, Kardash E, Chen S, Raz E, Lin F. Xu H, et al. Among authors: chen s. Development. 2012 Jan;139(1):57-62. doi: 10.1242/dev.073924. Epub 2011 Nov 17. Development. 2012. PMID: 22096073 Free PMC article.

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