Giangrande PH - Search Results

1

Intracellular delivery of RNA-based therapeutics using aptamers.

Thiel KW, Giangrande PH. Thiel KW, et al. Among authors: giangrande ph. Ther Deliv. 2010 Dec;1(6):849-61. doi: 10.4155/tde.10.61. Ther Deliv. 2010. PMID: 21643487 Free PMC article. Review.

2

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors.

Dassie JP, Liu XY, Thomas GS, Whitaker RM, Thiel KW, Stockdale KR, Meyerholz DK, McCaffrey AP, McNamara JO 2nd, Giangrande PH. Dassie JP, et al. Among authors: giangrande ph. Nat Biotechnol. 2009 Sep;27(9):839-49. doi: 10.1038/nbt.1560. Epub 2009 Aug 23. Nat Biotechnol. 2009. PMID: 19701187 Free PMC article.

3

Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers.

Thiel KW, Hernandez LI, Dassie JP, Thiel WH, Liu X, Stockdale KR, Rothman AM, Hernandez FJ, McNamara JO 2nd, Giangrande PH. Thiel KW, et al. Among authors: giangrande ph. Nucleic Acids Res. 2012 Jul;40(13):6319-37. doi: 10.1093/nar/gks294. Epub 2012 Mar 30. Nucleic Acids Res. 2012. PMID: 22467215 Free PMC article.

4

Cell-internalization SELEX: method for identifying cell-internalizing RNA aptamers for delivering siRNAs to target cells.

Thiel WH, Thiel KW, Flenker KS, Bair T, Dupuy AJ, McNamara JO 2nd, Miller FJ, Giangrande PH. Thiel WH, et al. Among authors: giangrande ph. Methods Mol Biol. 2015;1218:187-99. doi: 10.1007/978-1-4939-1538-5_11. Methods Mol Biol. 2015. PMID: 25319652 Free PMC article.

5

Therapeutic applications of DNA and RNA aptamers.

Thiel KW, Giangrande PH. Thiel KW, et al. Among authors: giangrande ph. Oligonucleotides. 2009 Sep;19(3):209-22. doi: 10.1089/oli.2009.0199. Oligonucleotides. 2009. PMID: 19653880 Free PMC article. Review.

6

Current progress on aptamer-targeted oligonucleotide therapeutics.

Dassie JP, Giangrande PH. Dassie JP, et al. Among authors: giangrande ph. Ther Deliv. 2013 Dec;4(12):1527-46. doi: 10.4155/tde.13.118. Ther Deliv. 2013. PMID: 24304250 Free PMC article. Review.

7

Method for Confirming Cytoplasmic Delivery of RNA Aptamers.

Dickey DD, Thomas GS, Dassie JP, Giangrande PH. Dickey DD, et al. Among authors: giangrande ph. Methods Mol Biol. 2016;1364:209-17. doi: 10.1007/978-1-4939-3112-5_17. Methods Mol Biol. 2016. PMID: 26472453 Free PMC article.

8

Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection.

Thiel WH, Bair T, Peek AS, Liu X, Dassie J, Stockdale KR, Behlke MA, Miller FJ Jr, Giangrande PH. Thiel WH, et al. Among authors: giangrande ph. PLoS One. 2012;7(9):e43836. doi: 10.1371/journal.pone.0043836. Epub 2012 Sep 4. PLoS One. 2012. PMID: 22962591 Free PMC article.

9

Oligonucleotide aptamers: A next-generation technology for the capture and detection of circulating tumor cells.

Dickey DD, Giangrande PH. Dickey DD, et al. Among authors: giangrande ph. Methods. 2016 Mar 15;97:94-103. doi: 10.1016/j.ymeth.2015.11.020. Epub 2015 Nov 26. Methods. 2016. PMID: 26631715 Free PMC article. Review.

10

Structural computational modeling of RNA aptamers.

Xu X, Dickey DD, Chen SJ, Giangrande PH. Xu X, et al. Among authors: giangrande ph. Methods. 2016 Jul 1;103:175-9. doi: 10.1016/j.ymeth.2016.03.004. Epub 2016 Mar 10. Methods. 2016. PMID: 26972787 Free PMC article.

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