Chen CY - Search Results

1

Antitumor agents 288: design, synthesis, SAR, and biological studies of novel heteroatom-incorporated antofine and cryptopleurine analogues as potent and selective antitumor agents.

Yang X, Shi Q, Yang SC, Chen CY, Yu SL, Bastow KF, Morris-Natschke SL, Wu PC, Lai CY, Wu TS, Pan SL, Teng CM, Lin JC, Yang PC, Lee KH. Yang X, et al. Among authors: chen cy. J Med Chem. 2011 Jul 28;54(14):5097-107. doi: 10.1021/jm200330s. Epub 2011 Jun 28. J Med Chem. 2011. PMID: 21668000 Free PMC article.

2

Antitumor agents 295. E-ring hydroxylated antofine and cryptopleurine analogues as antiproliferative agents: design, synthesis, and mechanistic studies.

Yang X, Shi Q, Lai CY, Chen CY, Ohkoshi E, Yang SC, Wang CY, Bastow KF, Wu TS, Pan SL, Teng CM, Yang PC, Lee KH. Yang X, et al. Among authors: chen cy. J Med Chem. 2012 Aug 9;55(15):6751-61. doi: 10.1021/jm3001218. Epub 2012 Jul 23. J Med Chem. 2012. PMID: 22823514 Free PMC article.

3

Tid1-L inhibits EGFR signaling in lung adenocarcinoma by enhancing EGFR Ubiquitinylation and degradation.

Chen CY, Jan CI, Lo JF, Yang SC, Chang YL, Pan SH, Wang WL, Hong TM, Yang PC. Chen CY, et al. Cancer Res. 2013 Jul 1;73(13):4009-19. doi: 10.1158/0008-5472.CAN-12-4066. Epub 2013 May 22. Cancer Res. 2013. PMID: 23698466

4

The antitumor agent PBT-1 directly targets HSP90 and hnRNP A2/B1 and inhibits lung adenocarcinoma growth and metastasis.

Chen CY, Yang SC, Lee KH, Yang X, Wei LY, Chow LP, Wang TC, Hong TM, Lin JC, Kuan C, Yang PC. Chen CY, et al. J Med Chem. 2014 Feb 13;57(3):677-85. doi: 10.1021/jm401686b. Epub 2014 Jan 31. J Med Chem. 2014. PMID: 24428777 Free PMC article.

5

Overcoming EGFR T790M-based Tyrosine Kinase Inhibitor Resistance with an Allele-specific DNAzyme.

Lai WY, Chen CY, Yang SC, Wu JY, Chang CJ, Yang PC, Peck K. Lai WY, et al. Among authors: chen cy. Mol Ther Nucleic Acids. 2014 Mar 4;3(3):e150. doi: 10.1038/mtna.2014.3. Mol Ther Nucleic Acids. 2014. PMID: 24594844 Free PMC article.

6

Small Molecule T315 Promotes Casitas B-Lineage Lymphoma-Dependent Degradation of Epidermal Growth Factor Receptor via Y1045 Autophosphorylation.

Huang KY, Kao SH, Wang WL, Chen CY, Hsiao TH, Salunke SB, Chen JJ, Su KY, Yang SC, Hong TM, Chen CS, Yang PC. Huang KY, et al. Among authors: chen jj, chen cs, chen cy. Am J Respir Crit Care Med. 2016 Apr 1;193(7):753-66. doi: 10.1164/rccm.201502-0250OC. Am J Respir Crit Care Med. 2016. PMID: 26583948

7

Integrated Omics Analysis of Non-Small-Cell Lung Cancer Cells Harboring the EGFR C797S Mutation Reveals the Potential of AXL as a Novel Therapeutic Target in TKI-Resistant Lung Cancer.

Wang TH, Wu CC, Huang KY, Leu YL, Yang SC, Chen CL, Chen CY. Wang TH, et al. Among authors: chen cl, chen cy. Cancers (Basel). 2020 Dec 31;13(1):111. doi: 10.3390/cancers13010111. Cancers (Basel). 2020. PMID: 33396393 Free PMC article.

8

Psorachromene induces apoptosis and suppresses tumor growth in NSCLC cells harboring EGFR L858R/T790M/C797S.

Wang TH, Leu YL, Chen CC, Li HJ, Yang SC, Huang KY, Chen CY. Wang TH, et al. Among authors: chen cc, chen cy. Phytother Res. 2022 May;36(5):2116-2126. doi: 10.1002/ptr.7432. Epub 2022 Mar 1. Phytother Res. 2022. PMID: 35229911

9

PM2.5 promotes lung cancer progression through activation of the AhR-TMPRSS2-IL18 pathway.

Wang TH, Huang KY, Chen CC, Chang YH, Chen HY, Hsueh C, Liu YT, Yang SC, Yang PC, Chen CY. Wang TH, et al. Among authors: chen cc, chen hy, chen cy. EMBO Mol Med. 2023 Jun 7;15(6):e17014. doi: 10.15252/emmm.202217014. Epub 2023 Mar 28. EMBO Mol Med. 2023. PMID: 36975376 Free PMC article.

10

Development of nanoparticles incorporated with quercetin and ACE2-membrane as a novel therapy for COVID-19.

Fang JY, Huang KY, Wang TH, Lin ZC, Chen CC, Chang SY, Chen EL, Chao TL, Yang SC, Yang PC, Chen CY. Fang JY, et al. Among authors: chen cc, chen cy, chen el. J Nanobiotechnology. 2024 Apr 12;22(1):169. doi: 10.1186/s12951-024-02435-2. J Nanobiotechnology. 2024. PMID: 38609998 Free PMC article.

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