Yang X - Search Results

1

Antitumor agents 288: design, synthesis, SAR, and biological studies of novel heteroatom-incorporated antofine and cryptopleurine analogues as potent and selective antitumor agents.

Yang X, Shi Q, Yang SC, Chen CY, Yu SL, Bastow KF, Morris-Natschke SL, Wu PC, Lai CY, Wu TS, Pan SL, Teng CM, Lin JC, Yang PC, Lee KH. Yang X, et al. Among authors: yang pc, yang sc. J Med Chem. 2011 Jul 28;54(14):5097-107. doi: 10.1021/jm200330s. Epub 2011 Jun 28. J Med Chem. 2011. PMID: 21668000 Free PMC article.

2

Design and one-pot synthesis of new 7-acyl camptothecin derivatives as potent cytotoxic agents.

Liu YQ, Dai W, Wang CY, Morris-Natschke SL, Zhou XW, Yang L, Yang XM, Li WQ, Lee KH. Liu YQ, et al. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7659-61. doi: 10.1016/j.bmcl.2012.10.002. Epub 2012 Oct 11. Bioorg Med Chem Lett. 2012. PMID: 23102893

3

Synthesis and mechanistic studies of novel spin-labeled combretastatin derivatives as potential antineoplastic agents.

Liu YQ, Li XJ, Zhao CY, Nan X, Tian J, Morris-Natschke SL, Zhang ZJ, Yang XM, Yang L, Li LH, Zhou XW, Lee KH. Liu YQ, et al. Among authors: yang xm, yang l. Bioorg Med Chem. 2013 Mar 1;21(5):1248-56. doi: 10.1016/j.bmc.2012.12.046. Epub 2013 Jan 9. Bioorg Med Chem. 2013. PMID: 23369687

4

Design, synthesis, mechanisms of action, and toxicity of novel 20(s)-sulfonylamidine derivatives of camptothecin as potent antitumor agents.

Wang MJ, Liu YQ, Chang LC, Wang CY, Zhao YL, Zhao XB, Qian K, Nan X, Yang L, Yang XM, Hung HY, Yang JS, Kuo DH, Goto M, Morris-Natschke SL, Pan SL, Teng CM, Kuo SC, Wu TS, Wu YC, Lee KH. Wang MJ, et al. Among authors: yang xm, yang l, yang js. J Med Chem. 2014 Jul 24;57(14):6008-18. doi: 10.1021/jm5003588. Epub 2014 Jul 8. J Med Chem. 2014. PMID: 25003995 Free PMC article.

5

Alkaloids from Oxytropis ochrocephala and antiproliferative activity of sophoridine derivatives against cancer cell lines.

Tan CJ, Zhao Y, Goto M, Hsieh KY, Yang XM, Morris-Natschke SL, Liu LN, Zhao BY, Lee KH. Tan CJ, et al. Bioorg Med Chem Lett. 2016 Mar 1;26(5):1495-7. doi: 10.1016/j.bmcl.2015.09.010. Epub 2015 Sep 5. Bioorg Med Chem Lett. 2016. PMID: 26865176 Free PMC article.

6

Antitumor agents 295. E-ring hydroxylated antofine and cryptopleurine analogues as antiproliferative agents: design, synthesis, and mechanistic studies.

Yang X, Shi Q, Lai CY, Chen CY, Ohkoshi E, Yang SC, Wang CY, Bastow KF, Wu TS, Pan SL, Teng CM, Yang PC, Lee KH. Yang X, et al. Among authors: yang pc, yang sc. J Med Chem. 2012 Aug 9;55(15):6751-61. doi: 10.1021/jm3001218. Epub 2012 Jul 23. J Med Chem. 2012. PMID: 22823514 Free PMC article.

7

Synthesis and biological evaluation of novel spin labeled 18β-glycyrrhetinic acid derivatives.

Liu Y, Qian K, Wang CY, Chen CH, Yang X, Lee KH. Liu Y, et al. Among authors: yang x. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7530-3. doi: 10.1016/j.bmcl.2012.10.041. Epub 2012 Oct 16. Bioorg Med Chem Lett. 2012. PMID: 23122524

8

Fluorinated betulinic acid derivatives and evaluation of their anti-HIV activity.

Li J, Goto M, Yang X, Morris-Natschke SL, Huang L, Chen CH, Lee KH. Li J, et al. Among authors: yang x. Bioorg Med Chem Lett. 2016 Jan 1;26(1):68-71. doi: 10.1016/j.bmcl.2015.11.029. Epub 2015 Nov 11. Bioorg Med Chem Lett. 2016. PMID: 26598461 Free PMC article.

9

Structure-activity relationships of cryptopleurine analogs with E-ring modifications as anti-hepatitis C virus agents.

Wang Y, Chen SR, Yang X, Lee KH, Cheng YC. Wang Y, et al. Among authors: yang x. Bioorg Med Chem. 2018 Feb 1;26(3):630-636. doi: 10.1016/j.bmc.2017.12.027. Epub 2017 Dec 20. Bioorg Med Chem. 2018. PMID: 29317151 Free PMC article.

10

Discovery and synthesis of novel beesioside I derivatives with potent anti-HIV activity.

Wu H, Ma G, Yang Q, Zhu Y, Huang L, Tian Y, Yang X, Zhang M, Chen CH, Morris-Natschke SL, Yang M, Xu X, Lee KH. Wu H, et al. Among authors: yang q, yang m, yang x. Eur J Med Chem. 2019 Mar 15;166:159-166. doi: 10.1016/j.ejmech.2019.01.020. Epub 2019 Jan 10. Eur J Med Chem. 2019. PMID: 30703659 Free PMC article.

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