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Page 1
Stress and mTORture signaling.
Reiling JH, Sabatini DM. Reiling JH, et al. Among authors: sabatini dm. Oncogene. 2006 Oct 16;25(48):6373-83. doi: 10.1038/sj.onc.1209889. Oncogene. 2006. PMID: 17041623 Review.
Increased mTORC1 signaling UPRegulates stress.
Reiling JH, Sabatini DM. Reiling JH, et al. Among authors: sabatini dm. Mol Cell. 2008 Mar 14;29(5):533-5. doi: 10.1016/j.molcel.2008.02.011. Mol Cell. 2008. PMID: 18342598 Free article.
Highly parallel identification of essential genes in cancer cells.
Luo B, Cheung HW, Subramanian A, Sharifnia T, Okamoto M, Yang X, Hinkle G, Boehm JS, Beroukhim R, Weir BA, Mermel C, Barbie DA, Awad T, Zhou X, Nguyen T, Piqani B, Li C, Golub TR, Meyerson M, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE. Luo B, et al. Among authors: sabatini dm. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20380-5. doi: 10.1073/pnas.0810485105. Epub 2008 Dec 17. Proc Natl Acad Sci U S A. 2008. PMID: 19091943 Free PMC article.
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.
Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, Silver SJ, Weir BA, Reiling JH, Sheng Q, Gupta PB, Wadlow RC, Le H, Hoersch S, Wittner BS, Ramaswamy S, Livingston DM, Sabatini DM, Meyerson M, Thomas RK, Lander ES, Mesirov JP, Root DE, Gilliland DG, Jacks T, Hahn WC. Barbie DA, et al. Among authors: sabatini dm. Nature. 2009 Nov 5;462(7269):108-12. doi: 10.1038/nature08460. Epub 2009 Oct 21. Nature. 2009. PMID: 19847166 Free PMC article.
mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis.
Laplante M, Sabatini DM. Laplante M, et al. Among authors: sabatini dm. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3281-2. doi: 10.1073/pnas.1000323107. Epub 2010 Feb 18. Proc Natl Acad Sci U S A. 2010. PMID: 20167806 Free PMC article. No abstract available.
289 results