De Pascale G - Search Results

1

Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole.

Spitzer M, Griffiths E, Blakely KM, Wildenhain J, Ejim L, Rossi L, De Pascale G, Curak J, Brown E, Tyers M, Wright GD. Spitzer M, et al. Among authors: de pascale g. Mol Syst Biol. 2011 Jun 21;7:499. doi: 10.1038/msb.2011.31. Mol Syst Biol. 2011. PMID: 21694716 Free PMC article.

2

A forward chemical screen identifies antibiotic adjuvants in Escherichia coli.

Taylor PL, Rossi L, De Pascale G, Wright GD. Taylor PL, et al. Among authors: de pascale g. ACS Chem Biol. 2012 Sep 21;7(9):1547-55. doi: 10.1021/cb300269g. Epub 2012 Jun 22. ACS Chem Biol. 2012. PMID: 22698393

3

Identification and characterization of new inhibitors of fungal homoserine kinase.

De Pascale G, Griffiths EJ, Shakya T, Nazi I, Wright GD. De Pascale G, et al. Chembiochem. 2011 May 16;12(8):1179-82. doi: 10.1002/cbic.201100121. Epub 2011 Apr 28. Chembiochem. 2011. PMID: 21538764 No abstract available.

4

Antibiotic resistance by enzyme inactivation: from mechanisms to solutions.

De Pascale G, Wright GD. De Pascale G, et al. Chembiochem. 2010 Jul 5;11(10):1325-34. doi: 10.1002/cbic.201000067. Chembiochem. 2010. PMID: 20564281 Review. No abstract available.

5

Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance.

King AM, Reid-Yu SA, Wang W, King DT, De Pascale G, Strynadka NC, Walsh TR, Coombes BK, Wright GD. King AM, et al. Among authors: de pascale g. Nature. 2014 Jun 26;510(7506):503-6. doi: 10.1038/nature13445. Nature. 2014. PMID: 24965651 Free PMC article.

6

A Common Platform for Antibiotic Dereplication and Adjuvant Discovery.

Cox G, Sieron A, King AM, De Pascale G, Pawlowski AC, Koteva K, Wright GD. Cox G, et al. Among authors: de pascale g. Cell Chem Biol. 2017 Jan 19;24(1):98-109. doi: 10.1016/j.chembiol.2016.11.011. Epub 2016 Dec 22. Cell Chem Biol. 2017. PMID: 28017602 Free article.

7

Inactivation of the lipopeptide antibiotic daptomycin by hydrolytic mechanisms.

D'Costa VM, Mukhtar TA, Patel T, Koteva K, Waglechner N, Hughes DW, Wright GD, De Pascale G. D'Costa VM, et al. Among authors: de pascale g. Antimicrob Agents Chemother. 2012 Feb;56(2):757-64. doi: 10.1128/AAC.05441-11. Epub 2011 Nov 14. Antimicrob Agents Chemother. 2012. PMID: 22083474 Free PMC article.

8

β-Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents.

De Pascale G, Nazi I, Harrison PH, Wright GD. De Pascale G, et al. J Antibiot (Tokyo). 2011 Jul;64(7):483-7. doi: 10.1038/ja.2011.37. Epub 2011 Apr 27. J Antibiot (Tokyo). 2011. PMID: 21522158

9

The comprehensive antibiotic resistance database.

McArthur AG, Waglechner N, Nizam F, Yan A, Azad MA, Baylay AJ, Bhullar K, Canova MJ, De Pascale G, Ejim L, Kalan L, King AM, Koteva K, Morar M, Mulvey MR, O'Brien JS, Pawlowski AC, Piddock LJ, Spanogiannopoulos P, Sutherland AD, Tang I, Taylor PL, Thaker M, Wang W, Yan M, Yu T, Wright GD. McArthur AG, et al. Among authors: de pascale g. Antimicrob Agents Chemother. 2013 Jul;57(7):3348-57. doi: 10.1128/AAC.00419-13. Epub 2013 May 6. Antimicrob Agents Chemother. 2013. PMID: 23650175 Free PMC article.

10

Diversity-oriented synthesis and preliminary biological screening of highly substituted five-membered lactones and lactams originating from an allyboration of aldehydes and imines.

Elford TG, Ulaczyk-Lesanko A, De Pascale G, Wright GD, Hall DG. Elford TG, et al. Among authors: de pascale g. J Comb Chem. 2009 Jan-Feb;11(1):155-68. doi: 10.1021/cc8001487. J Comb Chem. 2009. PMID: 19072614

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