Rodriguez-Gonzalez A - Search Results

1

Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells.

Aldana-Masangkay GI, Rodriguez-Gonzalez A, Lin T, Ikeda AK, Hsieh YT, Kim YM, Lomenick B, Okemoto K, Landaw EM, Wang D, Mazitschek R, Bradner JE, Sakamoto KM. Aldana-Masangkay GI, et al. Leuk Lymphoma. 2011 Aug;52(8):1544-55. doi: 10.3109/10428194.2011.570821. Epub 2011 Jun 23. Leuk Lymphoma. 2011. PMID: 21699378 Free PMC article.

2

Role of the aggresome pathway in cancer: targeting histone deacetylase 6-dependent protein degradation.

Rodriguez-Gonzalez A, Lin T, Ikeda AK, Simms-Waldrip T, Fu C, Sakamoto KM. Rodriguez-Gonzalez A, et al. Cancer Res. 2008 Apr 15;68(8):2557-60. doi: 10.1158/0008-5472.CAN-07-5989. Cancer Res. 2008. PMID: 18413721 Review.

3

The aggresome pathway as a target for therapy in hematologic malignancies.

Simms-Waldrip T, Rodriguez-Gonzalez A, Lin T, Ikeda AK, Fu C, Sakamoto KM. Simms-Waldrip T, et al. Mol Genet Metab. 2008 Jul;94(3):283-6. doi: 10.1016/j.ymgme.2008.03.012. Epub 2008 May 9. Mol Genet Metab. 2008. PMID: 18472289 Free PMC article. Review.

4

Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer.

Rodriguez-Gonzalez A, Cyrus K, Salcius M, Kim K, Crews CM, Deshaies RJ, Sakamoto KM. Rodriguez-Gonzalez A, et al. Oncogene. 2008 Dec 4;27(57):7201-11. doi: 10.1038/onc.2008.320. Epub 2008 Sep 15. Oncogene. 2008. PMID: 18794799 Free PMC article.

5

Choline kinase inhibition induces the increase in ceramides resulting in a highly specific and selective cytotoxic antitumoral strategy as a potential mechanism of action.

Rodríguez-González A, Ramirez de Molina A, Fernández F, Lacal JC. Rodríguez-González A, et al. Oncogene. 2004 Oct 28;23(50):8247-59. doi: 10.1038/sj.onc.1208045. Oncogene. 2004. PMID: 15378008

6

Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells.

Rodríguez-González A, Ramírez de Molina A, Fernández F, Ramos MA, del Carmen Núñez M, Campos J, Lacal JC. Rodríguez-González A, et al. Oncogene. 2003 Dec 4;22(55):8803-12. doi: 10.1038/sj.onc.1207062. Oncogene. 2003. PMID: 14654777

7

Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression.

Ramírez de Molina A, Báñez-Coronel M, Gutiérrez R, Rodríguez-González A, Olmeda D, Megías D, Lacal JC. Ramírez de Molina A, et al. Cancer Res. 2004 Sep 15;64(18):6732-9. doi: 10.1158/0008-5472.CAN-04-0489. Cancer Res. 2004. PMID: 15374991

8

Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers.

Ramírez de Molina A, Rodríguez-González A, Gutiérrez R, Martínez-Piñeiro L, Sánchez J, Bonilla F, Rosell R, Lacal J. Ramírez de Molina A, et al. Biochem Biophys Res Commun. 2002 Aug 23;296(3):580-3. doi: 10.1016/s0006-291x(02)00920-8. Biochem Biophys Res Commun. 2002. PMID: 12176020

9

Phospholipase D and choline kinase: their role in cancer development and their potential as drug targets.

Rodríguez-González A, Ramírez de Molina A, Benítez-Rajal J, Lacal JC. Rodríguez-González A, et al. Prog Cell Cycle Res. 2003;5:191-201. Prog Cell Cycle Res. 2003. PMID: 14593713 Review.

10

From Ras signalling to ChoK inhibitors: a further advance in anticancer drug design.

Ramírez de Molina A, Rodríguez-González A, Lacal JC. Ramírez de Molina A, et al. Cancer Lett. 2004 Apr 8;206(2):137-48. doi: 10.1016/j.canlet.2003.08.031. Cancer Lett. 2004. PMID: 15013519 Review.

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