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Page 1
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses.
Zak DE, Schmitz F, Gold ES, Diercks AH, Peschon JJ, Valvo JS, Niemistö A, Podolsky I, Fallen SG, Suen R, Stolyar T, Johnson CD, Kennedy KA, Hamilton MK, Siggs OM, Beutler B, Aderem A. Zak DE, et al. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11536-41. doi: 10.1073/pnas.1107577108. Epub 2011 Jun 27. Proc Natl Acad Sci U S A. 2011. PMID: 21709223 Free PMC article.
The Innate Immune Database (IIDB).
Korb M, Rust AG, Thorsson V, Battail C, Li B, Hwang D, Kennedy KA, Roach JC, Rosenberger CM, Gilchrist M, Zak D, Johnson C, Marzolf B, Aderem A, Shmulevich I, Bolouri H. Korb M, et al. BMC Immunol. 2008 Mar 5;9:7. doi: 10.1186/1471-2172-9-7. BMC Immunol. 2008. PMID: 18321385 Free PMC article.
Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics.
Ramsey SA, Klemm SL, Zak DE, Kennedy KA, Thorsson V, Li B, Gilchrist M, Gold ES, Johnson CD, Litvak V, Navarro G, Roach JC, Rosenberger CM, Rust AG, Yudkovsky N, Aderem A, Shmulevich I. Ramsey SA, et al. Among authors: zak de. PLoS Comput Biol. 2008 Mar 21;4(3):e1000021. doi: 10.1371/journal.pcbi.1000021. PLoS Comput Biol. 2008. PMID: 18369420 Free PMC article.
Systems biology of innate immunity.
Zak DE, Aderem A. Zak DE, et al. Immunol Rev. 2009 Jan;227(1):264-82. doi: 10.1111/j.1600-065X.2008.00721.x. Immunol Rev. 2009. PMID: 19120490 Free PMC article. Review.
A systems view of host defense.
Zak DE, Aderem A. Zak DE, et al. Nat Biotechnol. 2009 Nov;27(11):999-1001. doi: 10.1038/nbt1109-999. Nat Biotechnol. 2009. PMID: 19898453 Free PMC article.
Merck Ad5/HIV induces broad innate immune activation that predicts CD8⁺ T-cell responses but is attenuated by preexisting Ad5 immunity.
Zak DE, Andersen-Nissen E, Peterson ER, Sato A, Hamilton MK, Borgerding J, Krishnamurty AT, Chang JT, Adams DJ, Hensley TR, Salter AI, Morgan CA, Duerr AC, De Rosa SC, Aderem A, McElrath MJ. Zak DE, et al. Among authors: de rosa sc. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):E3503-12. doi: 10.1073/pnas.1208972109. Epub 2012 Nov 14. Proc Natl Acad Sci U S A. 2012. PMID: 23151505 Free PMC article.
Systems-level analysis of innate immunity.
Zak DE, Tam VC, Aderem A. Zak DE, et al. Annu Rev Immunol. 2014;32:547-77. doi: 10.1146/annurev-immunol-032713-120254. Annu Rev Immunol. 2014. PMID: 24655298 Free PMC article. Review.
52 results