Mitchison TJ - Search Results

1

Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics.

Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ. Orth JD, et al. Among authors: mitchison tj. Cancer Res. 2011 Jul 1;71(13):4608-16. doi: 10.1158/0008-5472.CAN-11-0412. Epub 2011 Jun 28. Cancer Res. 2011. PMID: 21712408 Free PMC article.

2

Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5.

Shi J, Orth JD, Mitchison T. Shi J, et al. Cancer Res. 2008 May 1;68(9):3269-76. doi: 10.1158/0008-5472.CAN-07-6699. Cancer Res. 2008. PMID: 18451153

3

Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate.

Orth JD, Tang Y, Shi J, Loy CT, Amendt C, Wilm C, Zenke FT, Mitchison TJ. Orth JD, et al. Among authors: mitchison tj. Mol Cancer Ther. 2008 Nov;7(11):3480-9. doi: 10.1158/1535-7163.MCT-08-0684. Epub 2008 Oct 30. Mol Cancer Ther. 2008. PMID: 18974392 Free PMC article.

4

Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.

Huang HC, Shi J, Orth JD, Mitchison TJ. Huang HC, et al. Among authors: mitchison tj. Cancer Cell. 2009 Oct 6;16(4):347-58. doi: 10.1016/j.ccr.2009.08.020. Cancer Cell. 2009. PMID: 19800579 Free PMC article.

5

An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor.

Tsui M, Xie T, Orth JD, Carpenter AE, Rudnicki S, Kim S, Shamu CE, Mitchison TJ. Tsui M, et al. Among authors: mitchison tj. PLoS One. 2009 Oct 5;4(10):e7339. doi: 10.1371/journal.pone.0007339. PLoS One. 2009. PMID: 19802393 Free PMC article.

6

Cell death when the SAC is out of commission.

Huang HC, Shi J, Orth JD, Mitchison TJ. Huang HC, et al. Among authors: mitchison tj. Cell Cycle. 2010 Jun 1;9(11):2049-50. doi: 10.4161/cc.9.11.11918. Epub 2010 Jun 1. Cell Cycle. 2010. PMID: 20559025 No abstract available.

7

Navitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL.

Shi J, Zhou Y, Huang HC, Mitchison TJ. Shi J, et al. Among authors: mitchison tj. Cancer Res. 2011 Jul 1;71(13):4518-26. doi: 10.1158/0008-5472.CAN-10-4336. Epub 2011 May 5. Cancer Res. 2011. PMID: 21546570 Free PMC article.

8

Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells.

Tang Y, Orth JD, Xie T, Mitchison TJ. Tang Y, et al. Among authors: mitchison tj. Cancer Lett. 2011 Nov 1;310(1):15-24. doi: 10.1016/j.canlet.2011.05.024. Epub 2011 Jun 24. Cancer Lett. 2011. PMID: 21782324 Free PMC article.

9

Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction.

Orth JD, Loewer A, Lahav G, Mitchison TJ. Orth JD, et al. Among authors: mitchison tj. Mol Biol Cell. 2012 Feb;23(4):567-76. doi: 10.1091/mbc.E11-09-0781. Epub 2011 Dec 14. Mol Biol Cell. 2012. PMID: 22171325 Free PMC article.

10

The proliferation rate paradox in antimitotic chemotherapy.

Mitchison TJ. Mitchison TJ. Mol Biol Cell. 2012 Jan;23(1):1-6. doi: 10.1091/mbc.E10-04-0335. Mol Biol Cell. 2012. PMID: 22210845 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

365 results

Search Page

Filters