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Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.
Alexander J, Lim D, Joughin BA, Hegemann B, Hutchins JR, Ehrenberger T, Ivins F, Sessa F, Hudecz O, Nigg EA, Fry AM, Musacchio A, Stukenberg PT, Mechtler K, Peters JM, Smerdon SJ, Yaffe MB. Alexander J, et al. Among authors: musacchio a. Sci Signal. 2011 Jun 28;4(179):ra42. doi: 10.1126/scisignal.2001796. Sci Signal. 2011. PMID: 21712545 Free PMC article.
Sgt1 is required for human kinetochore assembly.
Steensgaard P, Garrè M, Muradore I, Transidico P, Nigg EA, Kitagawa K, Earnshaw WC, Faretta M, Musacchio A. Steensgaard P, et al. Among authors: musacchio a. EMBO Rep. 2004 Jun;5(6):626-31. doi: 10.1038/sj.embor.7400154. Epub 2004 May 7. EMBO Rep. 2004. PMID: 15133482 Free PMC article.
Mechanism of Aurora B activation by INCENP and inhibition by hesperadin.
Sessa F, Mapelli M, Ciferri C, Tarricone C, Areces LB, Schneider TR, Stukenberg PT, Musacchio A. Sessa F, et al. Among authors: musacchio a. Mol Cell. 2005 Apr 29;18(3):379-91. doi: 10.1016/j.molcel.2005.03.031. Mol Cell. 2005. PMID: 15866179 Free article.
Discovery of selective aminothiazole aurora kinase inhibitors.
Andersen CB, Wan Y, Chang JW, Riggs B, Lee C, Liu Y, Sessa F, Villa F, Kwiatkowski N, Suzuki M, Nallan L, Heald R, Musacchio A, Gray NS. Andersen CB, et al. Among authors: musacchio a. ACS Chem Biol. 2008 Mar 20;3(3):180-92. doi: 10.1021/cb700200w. Epub 2008 Feb 29. ACS Chem Biol. 2008. PMID: 18307303
Molecular basis of drug resistance in aurora kinases.
Girdler F, Sessa F, Patercoli S, Villa F, Musacchio A, Taylor S. Girdler F, et al. Among authors: musacchio a. Chem Biol. 2008 Jun;15(6):552-62. doi: 10.1016/j.chembiol.2008.04.013. Chem Biol. 2008. PMID: 18559266
The structure of the GTPase-activating domain from p50rhoGAP.
Barrett T, Xiao B, Dodson EJ, Dodson G, Ludbrook SB, Nurmahomed K, Gamblin SJ, Musacchio A, Smerdon SJ, Eccleston JF. Barrett T, et al. Among authors: musacchio a. Nature. 1997 Jan 30;385(6615):458-61. doi: 10.1038/385458a0. Nature. 1997. PMID: 9009196
258 results