Smerdon SJ - Search Results

1

Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.

Alexander J, Lim D, Joughin BA, Hegemann B, Hutchins JR, Ehrenberger T, Ivins F, Sessa F, Hudecz O, Nigg EA, Fry AM, Musacchio A, Stukenberg PT, Mechtler K, Peters JM, Smerdon SJ, Yaffe MB. Alexander J, et al. Among authors: smerdon sj. Sci Signal. 2011 Jun 28;4(179):ra42. doi: 10.1126/scisignal.2001796. Sci Signal. 2011. PMID: 21712545 Free PMC article.

2

The use of in vitro peptide-library screens in the analysis of phosphoserine/threonine-binding domain structure and function.

Yaffe MB, Smerdon SJ. Yaffe MB, et al. Among authors: smerdon sj. Annu Rev Biophys Biomol Struct. 2004;33:225-44. doi: 10.1146/annurev.biophys.33.110502.133346. Annu Rev Biophys Biomol Struct. 2004. PMID: 15139812 Review.

3

Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of all human 14-3-3 isoforms.

Gardino AK, Smerdon SJ, Yaffe MB. Gardino AK, et al. Among authors: smerdon sj. Semin Cancer Biol. 2006 Jun;16(3):173-82. doi: 10.1016/j.semcancer.2006.03.007. Epub 2006 Apr 1. Semin Cancer Biol. 2006. PMID: 16678437 Review.

4

A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint.

van Vugt MA, Gardino AK, Linding R, Ostheimer GJ, Reinhardt HC, Ong SE, Tan CS, Miao H, Keezer SM, Li J, Pawson T, Lewis TA, Carr SA, Smerdon SJ, Brummelkamp TR, Yaffe MB. van Vugt MA, et al. Among authors: smerdon sj. PLoS Biol. 2010 Jan 26;8(1):e1000287. doi: 10.1371/journal.pbio.1000287. PLoS Biol. 2010. PMID: 20126263 Free PMC article.

5

Activation of the yeast Hippo pathway by phosphorylation-dependent assembly of signaling complexes.

Rock JM, Lim D, Stach L, Ogrodowicz RW, Keck JM, Jones MH, Wong CC, Yates JR 3rd, Winey M, Smerdon SJ, Yaffe MB, Amon A. Rock JM, et al. Among authors: smerdon sj. Science. 2013 May 17;340(6134):871-5. doi: 10.1126/science.1235822. Epub 2013 Apr 11. Science. 2013. PMID: 23579499 Free PMC article.

6

The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain.

Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K, Mohammad D, Cantley LC, Smerdon SJ, Yaffe MB. Elia AE, et al. Among authors: smerdon sj. Cell. 2003 Oct 3;115(1):83-95. doi: 10.1016/s0092-8674(03)00725-6. Cell. 2003. PMID: 14532005 Free article.

7

PhosphoSerine/threonine binding domains: you can't pSERious?

Yaffe MB, Smerdon SJ. Yaffe MB, et al. Among authors: smerdon sj. Structure. 2001 Mar 7;9(3):R33-8. doi: 10.1016/s0969-2126(01)00580-9. Structure. 2001. PMID: 11286893 Free article. Review.

8

The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms.

Durocher D, Taylor IA, Sarbassova D, Haire LF, Westcott SL, Jackson SP, Smerdon SJ, Yaffe MB. Durocher D, et al. Among authors: smerdon sj. Mol Cell. 2000 Nov;6(5):1169-82. doi: 10.1016/s1097-2765(00)00114-3. Mol Cell. 2000. PMID: 11106755 Free article.

9

The FHA domain in DNA repair and checkpoint signaling.

Durocher D, Smerdon SJ, Yaffe MB, Jackson SP. Durocher D, et al. Among authors: smerdon sj. Cold Spring Harb Symp Quant Biol. 2000;65:423-31. doi: 10.1101/sqb.2000.65.423. Cold Spring Harb Symp Quant Biol. 2000. PMID: 12760058 Review. No abstract available.

10

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks.

Stucki M, Clapperton JA, Mohammad D, Yaffe MB, Smerdon SJ, Jackson SP. Stucki M, et al. Among authors: smerdon sj. Cell. 2005 Dec 29;123(7):1213-26. doi: 10.1016/j.cell.2005.09.038. Cell. 2005. PMID: 16377563 Free article.

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