Krainc D - Search Results

1

Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease.

Xiang Z, Valenza M, Cui L, Leoni V, Jeong HK, Brilli E, Zhang J, Peng Q, Duan W, Reeves SA, Cattaneo E, Krainc D. Xiang Z, et al. Among authors: krainc d. J Neurosci. 2011 Jun 29;31(26):9544-53. doi: 10.1523/JNEUROSCI.1291-11.2011. J Neurosci. 2011. PMID: 21715619 Free PMC article.

2

Variants in ATP5F1B are associated with dominantly inherited dystonia.

Nasca A, Mencacci NE, Invernizzi F, Zech M, Keller Sarmiento IJ, Legati A, Frascarelli C, Bustos BI, Romito LM, Krainc D, Winkelmann J, Carecchio M, Nardocci N, Zorzi G, Prokisch H, Lubbe SJ, Garavaglia B, Ghezzi D. Nasca A, et al. Among authors: krainc d. Brain. 2023 Jul 3;146(7):2730-2738. doi: 10.1093/brain/awad068. Brain. 2023. PMID: 36860166 Free PMC article.

3

Genome-wide contribution of common short-tandem repeats to Parkinson's disease genetic risk.

Bustos BI, Billingsley K, Blauwendraat C, Gibbs JR, Gan-Or Z, Krainc D, Singleton AB, Lubbe SJ; International Parkinson’s Disease Genomics Consortium (IPDGC). Bustos BI, et al. Among authors: krainc d. Brain. 2023 Jan 5;146(1):65-74. doi: 10.1093/brain/awac301. Brain. 2023. PMID: 36347471 Free PMC article.

4

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease.

Dunah AW, Jeong H, Griffin A, Kim YM, Standaert DG, Hersch SM, Mouradian MM, Young AB, Tanese N, Krainc D. Dunah AW, et al. Among authors: krainc d. Science. 2002 Jun 21;296(5576):2238-43. doi: 10.1126/science.1072613. Epub 2002 May 2. Science. 2002. PMID: 11988536

5

Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease.

Borovecki F, Lovrecic L, Zhou J, Jeong H, Then F, Rosas HD, Hersch SM, Hogarth P, Bouzou B, Jensen RV, Krainc D. Borovecki F, et al. Among authors: krainc d. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11023-8. doi: 10.1073/pnas.0504921102. Epub 2005 Jul 25. Proc Natl Acad Sci U S A. 2005. PMID: 16043692 Free PMC article.

6

In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets.

Zhai W, Jeong H, Cui L, Krainc D, Tjian R. Zhai W, et al. Among authors: krainc d. Cell. 2005 Dec 29;123(7):1241-53. doi: 10.1016/j.cell.2005.10.030. Cell. 2005. PMID: 16377565 Free article.

7

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

Cui L, Jeong H, Borovecki F, Parkhurst CN, Tanese N, Krainc D. Cui L, et al. Among authors: krainc d. Cell. 2006 Oct 6;127(1):59-69. doi: 10.1016/j.cell.2006.09.015. Cell. 2006. PMID: 17018277 Free article.

8

Acetylation targets mutant huntingtin to autophagosomes for degradation.

Jeong H, Then F, Melia TJ Jr, Mazzulli JR, Cui L, Savas JN, Voisine C, Paganetti P, Tanese N, Hart AC, Yamamoto A, Krainc D. Jeong H, et al. Among authors: krainc d. Cell. 2009 Apr 3;137(1):60-72. doi: 10.1016/j.cell.2009.03.018. Cell. 2009. PMID: 19345187 Free PMC article.

9

Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors.

Kegel KB, Sapp E, Alexander J, Reeves P, Bleckmann D, Sobin L, Masso N, Valencia A, Jeong H, Krainc D, Palacino J, Curtis D, Kuhn R, Betschart C, Sena-Esteves M, Aronin N, Paganetti P, Difiglia M. Kegel KB, et al. Among authors: krainc d. Mol Neurodegener. 2010 Dec 14;5:58. doi: 10.1186/1750-1326-5-58. Mol Neurodegener. 2010. PMID: 21156064 Free PMC article.

10

Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells.

Seibler P, Graziotto J, Jeong H, Simunovic F, Klein C, Krainc D. Seibler P, et al. Among authors: krainc d. J Neurosci. 2011 Apr 20;31(16):5970-6. doi: 10.1523/JNEUROSCI.4441-10.2011. J Neurosci. 2011. PMID: 21508222 Free PMC article.

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