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Whole body cholesterol metabolism is impaired in Huntington's disease.
Leoni V, Mariotti C, Nanetti L, Salvatore E, Squitieri F, Bentivoglio AR, Bandettini di Poggio M, Piacentini S, Monza D, Valenza M, Cattaneo E, Di Donato S. Leoni V, et al. Neurosci Lett. 2011 May 2;494(3):245-9. doi: 10.1016/j.neulet.2011.03.025. Epub 2011 Mar 22. Neurosci Lett. 2011. PMID: 21406216
Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles for cholesterol delivery in Huntington's disease.
Birolini G, Valenza M, Ottonelli I, Passoni A, Favagrossa M, Duskey JT, Bombaci M, Vandelli MA, Colombo L, Bagnati R, Caccia C, Leoni V, Taroni F, Forni F, Ruozi B, Salmona M, Tosi G, Cattaneo E. Birolini G, et al. Among authors: leoni v. J Control Release. 2021 Feb 10;330:587-598. doi: 10.1016/j.jconrel.2020.12.051. Epub 2021 Jan 5. J Control Release. 2021. PMID: 33412229
Pitfalls in the detection of cholesterol in Huntington's disease models.
Marullo M, Valenza M, Leoni V, Caccia C, Scarlatti C, De Mario A, Zuccato C, Di Donato S, Carafoli E, Cattaneo E. Marullo M, et al. Among authors: leoni v. PLoS Curr. 2012 Oct 11;4:e505886e9a1968. doi: 10.1371/505886e9a1968. PLoS Curr. 2012. PMID: 23145355 Free PMC article.
Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice.
Valenza M, Chen JY, Di Paolo E, Ruozi B, Belletti D, Ferrari Bardile C, Leoni V, Caccia C, Brilli E, Di Donato S, Boido MM, Vercelli A, Vandelli MA, Forni F, Cepeda C, Levine MS, Tosi G, Cattaneo E. Valenza M, et al. Among authors: leoni v. EMBO Mol Med. 2015 Dec;7(12):1547-64. doi: 10.15252/emmm.201505413. EMBO Mol Med. 2015. PMID: 26589247 Free PMC article.
Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice.
Shankaran M, Di Paolo E, Leoni V, Caccia C, Ferrari Bardile C, Mohammed H, Di Donato S, Kwak S, Marchionini D, Turner S, Cattaneo E, Valenza M. Shankaran M, et al. Among authors: leoni v. Neurobiol Dis. 2017 Feb;98:66-76. doi: 10.1016/j.nbd.2016.11.013. Epub 2016 Nov 30. Neurobiol Dis. 2017. PMID: 27913290
Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice.
Birolini G, Valenza M, Di Paolo E, Vezzoli E, Talpo F, Maniezzi C, Caccia C, Leoni V, Taroni F, Bocchi VD, Conforti P, Sogne E, Petricca L, Cariulo C, Verani M, Caricasole A, Falqui A, Biella G, Cattaneo E. Birolini G, et al. Among authors: leoni v. EMBO Mol Med. 2020 Oct 7;12(10):e12519. doi: 10.15252/emmm.202012519. Epub 2020 Sep 22. EMBO Mol Med. 2020. PMID: 32959531 Free PMC article.
269 results